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• W1985546755 abstract "Fluctuations in the number of nascent RNA accurately reflect transcriptional activity. However, mathematical models predicting their distributions are difficult to solve analytically due to their non-Markovian nature stemming from transcriptional elongation. Here we circumvent this problem by deriving an exact relationship between the steady-state distribution of nascent RNA and the distribution of initiation times, which can be computed for any general initiation mechanism described by a set of first-order reactions. We test our theory using simulations and live cell imaging data." @default.
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• W1985546755 date "2012-09-01" @default.
• W1985546755 modified "2023-09-27" @default.
• W1985546755 title "Assessment and Recommendations of Compounding Education in AACP Member Institutions" @default.
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• W1985546755 doi "https://doi.org/10.5688/ajpe767s9" @default.
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