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- W1985565260 abstract "Inspired by the effect of norrisolide on the Golgi complex, we synthesized norrisolide probes that contain: the perhydroindane core of the parent natural product for Golgi localization, a crosslinking unit (aryl azide or epoxide) for covalent binding to the target, and a tag (biotin or iodine) for subsequent target purification. We found that biotin-containing probes 14, 20 and 24 induced inefficient Golgi vesiculation. However, the iodinated probe 25 induced extensive and irreversible Golgi fragmentation. This probe can be used for the isolation of the cellular target of norrisolide." @default.
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- W1985565260 date "2007-01-01" @default.
- W1985565260 modified "2023-09-25" @default.
- W1985565260 title "Trifunctional norrisolide probes for the study of Golgi vesiculation" @default.
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- W1985565260 doi "https://doi.org/10.1016/j.bmcl.2006.10.101" @default.
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