Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985606463> ?p ?o ?g. }
- W1985606463 endingPage "113" @default.
- W1985606463 startingPage "97" @default.
- W1985606463 abstract "MMPs (Matrix Metalloproteinases) are thought to play important roles in invasion processes (normal or pathological) by degrading basement membranes and extracellular matrix components which constitute a barrier for the migrating cells. Human trophoblast implantation is a physiological invasive process which is both spatially and temporally regulated. We have studied by immunohistochemistry, in situ hybridization and Northern blotting the expression of several MMPs (gelatinases A/B, MT1-MMP and stromelysin-3) and their specific inhibitors (TIMP-1, TIMP-2, TIMP-3) in first and third trimester human placenta in order to specify their role in vivo in this type of invasion. All the MMPs studied were highly expressed especially in first trimester invasive trophoblast cells. In contrast, TIMPs were strongly expressed in decidual cells especially during the third trimester of pregnancy. These data suggest that trophoblast implantation depends on a spatio-temporal balance between MMPs expressed by fetal cells and TIMPs expressed by maternal cells. As in other invasion processes, MMP expression is associated with an invasive phenotype." @default.
- W1985606463 created "2016-06-24" @default.
- W1985606463 creator A5027945913 @default.
- W1985606463 creator A5037460801 @default.
- W1985606463 creator A5047035945 @default.
- W1985606463 creator A5051374037 @default.
- W1985606463 date "1997-01-01" @default.
- W1985606463 modified "2023-09-24" @default.
- W1985606463 title "Expression of matrix metalloproteinases and their inhibitors during human placental development" @default.
- W1985606463 cites W1501988955 @default.
- W1985606463 cites W1505625682 @default.
- W1985606463 cites W1545521314 @default.
- W1985606463 cites W1593920002 @default.
- W1985606463 cites W1602981281 @default.
- W1985606463 cites W1649452503 @default.
- W1985606463 cites W1664158328 @default.
- W1985606463 cites W1668309971 @default.
- W1985606463 cites W1942960670 @default.
- W1985606463 cites W1949259756 @default.
- W1985606463 cites W1965389984 @default.
- W1985606463 cites W1966739459 @default.
- W1985606463 cites W1968449757 @default.
- W1985606463 cites W1968720464 @default.
- W1985606463 cites W1970668556 @default.
- W1985606463 cites W1971529761 @default.
- W1985606463 cites W1977019438 @default.
- W1985606463 cites W1979390430 @default.
- W1985606463 cites W1983335818 @default.
- W1985606463 cites W1984953670 @default.
- W1985606463 cites W1987912870 @default.
- W1985606463 cites W1991280760 @default.
- W1985606463 cites W1992989458 @default.
- W1985606463 cites W1994890460 @default.
- W1985606463 cites W2003204003 @default.
- W1985606463 cites W2006858696 @default.
- W1985606463 cites W2010027735 @default.
- W1985606463 cites W2012793423 @default.
- W1985606463 cites W2015359970 @default.
- W1985606463 cites W2015849738 @default.
- W1985606463 cites W2018941696 @default.
- W1985606463 cites W2020973067 @default.
- W1985606463 cites W2024318861 @default.
- W1985606463 cites W2025500658 @default.
- W1985606463 cites W2025571426 @default.
- W1985606463 cites W2035679663 @default.
- W1985606463 cites W2036017138 @default.
- W1985606463 cites W2036328142 @default.
- W1985606463 cites W2038092881 @default.
- W1985606463 cites W2042220015 @default.
- W1985606463 cites W2042234076 @default.
- W1985606463 cites W2043254359 @default.
- W1985606463 cites W2049220062 @default.
- W1985606463 cites W2057134714 @default.
- W1985606463 cites W2065531005 @default.
- W1985606463 cites W2071878806 @default.
- W1985606463 cites W2072438573 @default.
- W1985606463 cites W2075114300 @default.
- W1985606463 cites W2084356717 @default.
- W1985606463 cites W2086973678 @default.
- W1985606463 cites W2093293474 @default.
- W1985606463 cites W2113844812 @default.
- W1985606463 cites W2145854690 @default.
- W1985606463 cites W2155925117 @default.
- W1985606463 cites W2288606710 @default.
- W1985606463 cites W2344697123 @default.
- W1985606463 cites W2397048910 @default.
- W1985606463 cites W4240447878 @default.
- W1985606463 cites W4312567304 @default.
- W1985606463 doi "https://doi.org/10.1016/s0143-4004(97)80082-3" @default.
- W1985606463 hasPublicationYear "1997" @default.
- W1985606463 type Work @default.
- W1985606463 sameAs 1985606463 @default.
- W1985606463 citedByCount "2" @default.
- W1985606463 crossrefType "journal-article" @default.
- W1985606463 hasAuthorship W1985606463A5027945913 @default.
- W1985606463 hasAuthorship W1985606463A5037460801 @default.
- W1985606463 hasAuthorship W1985606463A5047035945 @default.
- W1985606463 hasAuthorship W1985606463A5051374037 @default.
- W1985606463 hasConcept C104317684 @default.
- W1985606463 hasConcept C109523444 @default.
- W1985606463 hasConcept C150194340 @default.
- W1985606463 hasConcept C172680121 @default.
- W1985606463 hasConcept C189165786 @default.
- W1985606463 hasConcept C2776193487 @default.
- W1985606463 hasConcept C2776232661 @default.
- W1985606463 hasConcept C2776953305 @default.
- W1985606463 hasConcept C2777495146 @default.
- W1985606463 hasConcept C2779234561 @default.
- W1985606463 hasConcept C2780197806 @default.
- W1985606463 hasConcept C2781107390 @default.
- W1985606463 hasConcept C2910246616 @default.
- W1985606463 hasConcept C54355233 @default.
- W1985606463 hasConcept C81439078 @default.
- W1985606463 hasConcept C86803240 @default.
- W1985606463 hasConcept C95444343 @default.
- W1985606463 hasConceptScore W1985606463C104317684 @default.
- W1985606463 hasConceptScore W1985606463C109523444 @default.
- W1985606463 hasConceptScore W1985606463C150194340 @default.