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• W1985646908 abstract "Letters15 July 1997Protracted Cholestatic Hepatitis after the Use of ProstataSaeed Hamid, MD, Sergio Rojter, MD, and John Vierling, MDSaeed Hamid, MDSouthwestern Medical Center; Dallas, TX 75235-9151Search for more papers by this author, Sergio Rojter, MDSouthwestern Medical Center; Dallas, TX 75235-9151Search for more papers by this author, and John Vierling, MDSouthwestern Medical Center; Dallas, TX 75235-9151Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-2-199707150-00033 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:One reason for the growing popularity of herbal medicines is the perception that these compounds are safe and free of side effects. We report a case of acute hepatitis caused by Prostata (Gero Vita International), an herbal preparation used to treat prostatic hypertrophy.A 65-year-old man with nocturia and hesitancy began taking Prostata, which had been ordered from a catalogue. Two weeks later, he developed jaundice and severe pruritus and stopped taking the medication. His abdomen was not tender, and his liver and spleen were not palpable. Biochemical findings were as follows: bilirubin level, 8.2 mg/dL; aspartate ...References1. Champault M, Patel JC, Bonnard AM. A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia. Br J Clin Pharmacol. 1984; 18:461-2. Google Scholar2. Kottra LL, Kappas A. Effect of estradiol on plasma disappearance rate of sulfobromophthalein in man. Arch Intern Med. 1966; 117:373-5. Google Scholar3. Haemmerli HU. Jaundice during pregnancy. In: Schiff L, ed. Diseases of the Liver. 4th ed. Philadelphia: JB Lippincott; 1975:1336-48. Google Scholar4. Dankoff JS. Near fatal liver dysfunction secondary to administration of flutamide for prostate cancer. J Urol. 1992; 148:1914. Google Scholar5. Marchetti B, Labrie F. Characteristics of flutamide action on prostate and testicular functions in the rat. J Steroid Biochem. 1988; 29:691-8. Google Scholar Author, Article, and Disclosure InformationAuthors: Saeed Hamid, MD; Sergio Rojter, MD; John Vierling, MDAffiliations: Southwestern Medical Center; Dallas, TX 75235-9151 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySaw Palmetto (Serenoa repens Sabal serrulatum)Herbs and their bioactive ingredients in cardio-protection: Underlying molecular mechanisms and evidences from clinical studiesSuspected adverse reactions to performance enhancing dietary supplements: Spontaneous reports from the Italian phytovigilance systemAdverse Effects of Nutraceuticals and Dietary SupplementsDrugs and ToxinsLiver toxicity related to herbs and dietary supplements: Online table of case reports. Part 2 of 5 seriesHerbal HepatotoxicityDaño hepático debido al uso de suplementos nutricionales y de herbolario: revisión de componentes individualesEuropean medicinal and edible plants associated with subacute and chronic toxicity part II: Plants with hepato-, neuro-, nephro- and immunotoxic effectsLiver injury due to herbal and dietary supplements: A review of individual ingredientsHerbal hepatotoxicity: current status, examples, and challengesHepatotoxicity of herbal and dietary supplements: an updateNatural Prevention of Prostatis [Prostate Inflammation] For 24 Male Subjects Over 6 MonthsHerbal Products and the Liver: A Review of Adverse Effects and MechanismsHepatotoxicity of Herbals and Dietary SupplementsHow to use the monographsHepatic injury due to drugs, herbal compounds, chemicals and toxinsAcute pancreatitis with saw palmetto use: a case reportWhat Do I Tell Patients About Saw Palmetto for Benign Prostatic Hyperplasia?A Possible Case of Saw Palmetto–Induced PancreatitisAcute liver damage due to Serenoa repens: a case reportUse of Herbal Products and Potential Interactions in Patients With Cardiovascular DiseasesA detailed safety assessment of a saw palmetto extractA case of vanishing bile duct syndrome and IBD secondary to Hodgkin's lymphomaA prospective study of the efficacy of Serenoa repens, Tamsulosin, and Serenoa repens plus Tamsulosin treatment for patients with benign prostate hyperplasiaHerbal medicine in the treatment of liver diseasesHepatotoxicity potential of Saw Palmetto (Serenoa repens) in ratsHepatic ToxicologySaw Palmetto-induced PancreatitisHerbal hepatotoxicityHerbal Product Contamination and ToxicitySystematic review: hepatotoxic events associated with herbal medicinal productsHepatotoxicity and complementary and alternative medicinesHerbs for Benign Prostatic HyperplasiaHerbal medicines: Poisons or potions?Editorial: Cardioprotective Effects of ω-3 Fatty Acids: A Critical Review That Should Be Read by a Wide Range of Health ProfessionalsClinincal Observations: Nutrient Supplements in Clinical CareHerbal hepatotoxicity: An expanding but poorly defined problemHepatotoxicity of botanicalsLIVER INJURY FROM HERBS AND OTHER BOTANICALSHerbal medicineSerenoa repensSaw Palmetto 15 July 1997Volume 127, Issue 2Page: 169-170KeywordsAntibodiesBilirubinEstrogensHepatitisHepatitis C virusLiverLiver diseasesLiver fibrosisLymphocytesTestosterone ePublished: 15 August 2000 Issue Published: 15 July 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ..." @default.
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