FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985654472> ?p ?o ?g. }

• W1985654472 endingPage "5413" @default.
• W1985654472 startingPage "5405" @default.
• W1985654472 abstract "An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent studies. However, identification of the critical molecular components of the neural matrix that mediate these processes is far from complete. Of particular interest is the perineuronal net (PN), an extracellular matrix component found surrounding the cell body and proximal neurites of a subset of neurons. Because of the apposition of the PN to synapses and expression of this structure coincident with the close of the critical period, it has been hypothesized that nets could play uniquely important roles in synapse stabilization and maturation. Interestingly, previous work has also shown that expression of PNs is dependent on appropriate sensory stimulation in the visual system. Here, we investigated whether PNs in the mouse barrel cortex are expressed in an activity-dependent manner by manipulating sensory input through whisker trimming. Importantly, this manipulation did not lead to a global loss of PNs but instead led to a specific decrease in PNs, detected with the antibody Cat-315, in layer IV of the barrel cortex. In addition, we identified a key activity-regulated component of PNs is the proteoglycan aggrecan. We also demonstrate that these Cat-315-positive neurons virtually all also express parvalbumin. Together, these data are in support of an important role for aggrecan in the activity-dependent formation of PNs on parvalbumin-expressing cells and suggest a role for expression of these nets in regulating the close of the critical period." @default.
• W1985654472 created "2016-06-24" @default.
• W1985654472 creator A5003238248 @default.
• W1985654472 creator A5033389134 @default.
• W1985654472 creator A5058534161 @default.
• W1985654472 creator A5077250479 @default.
• W1985654472 creator A5077722727 @default.
• W1985654472 date "2007-05-16" @default.
• W1985654472 modified "2023-09-27" @default.
• W1985654472 title "Sensory Deprivation Alters Aggrecan and Perineuronal Net Expression in the Mouse Barrel Cortex" @default.
• W1985654472 cites W1484033711 @default.
• W1985654472 cites W1488311471 @default.
• W1985654472 cites W1565093490 @default.
• W1985654472 cites W1839558765 @default.
• W1985654472 cites W1870538900 @default.
• W1985654472 cites W1883330555 @default.
• W1985654472 cites W1923448222 @default.
• W1985654472 cites W1963685656 @default.
• W1985654472 cites W1966167828 @default.
• W1985654472 cites W1968455009 @default.
• W1985654472 cites W1974815300 @default.
• W1985654472 cites W1983683998 @default.
• W1985654472 cites W1986126224 @default.
• W1985654472 cites W1993916224 @default.
• W1985654472 cites W1993936506 @default.
• W1985654472 cites W1995089204 @default.
• W1985654472 cites W2012993742 @default.
• W1985654472 cites W2023003530 @default.
• W1985654472 cites W2026158445 @default.
• W1985654472 cites W2027419157 @default.
• W1985654472 cites W2032124585 @default.
• W1985654472 cites W2034204817 @default.
• W1985654472 cites W2035496764 @default.
• W1985654472 cites W2045100245 @default.
• W1985654472 cites W2055559689 @default.
• W1985654472 cites W2062813684 @default.
• W1985654472 cites W2065585647 @default.
• W1985654472 cites W2071526203 @default.
• W1985654472 cites W2077729437 @default.
• W1985654472 cites W2077969408 @default.
• W1985654472 cites W2081655757 @default.
• W1985654472 cites W2085209794 @default.
• W1985654472 cites W2088475496 @default.
• W1985654472 cites W2091187766 @default.
• W1985654472 cites W2093539222 @default.
• W1985654472 cites W2099040370 @default.
• W1985654472 cites W2108841190 @default.
• W1985654472 cites W2111405228 @default.
• W1985654472 cites W2117910613 @default.
• W1985654472 cites W2120149411 @default.
• W1985654472 cites W2120301129 @default.
• W1985654472 cites W2129972752 @default.
• W1985654472 cites W2153572755 @default.
• W1985654472 cites W2157282099 @default.
• W1985654472 cites W2157352643 @default.
• W1985654472 cites W2159967267 @default.
• W1985654472 cites W2325060126 @default.
• W1985654472 cites W235963444 @default.
• W1985654472 cites W48695541 @default.
• W1985654472 doi "https://doi.org/10.1523/jneurosci.5425-06.2007" @default.
• W1985654472 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6672348" @default.
• W1985654472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17507562" @default.
• W1985654472 hasPublicationYear "2007" @default.
• W1985654472 type Work @default.
• W1985654472 sameAs 1985654472 @default.
• W1985654472 citedByCount "231" @default.
• W1985654472 countsByYear W19856544722012 @default.
• W1985654472 countsByYear W19856544722013 @default.
• W1985654472 countsByYear W19856544722014 @default.
• W1985654472 countsByYear W19856544722015 @default.
• W1985654472 countsByYear W19856544722016 @default.
• W1985654472 countsByYear W19856544722017 @default.
• W1985654472 countsByYear W19856544722018 @default.
• W1985654472 countsByYear W19856544722019 @default.
• W1985654472 countsByYear W19856544722020 @default.
• W1985654472 countsByYear W19856544722021 @default.
• W1985654472 countsByYear W19856544722022 @default.
• W1985654472 countsByYear W19856544722023 @default.
• W1985654472 crossrefType "journal-article" @default.
• W1985654472 hasAuthorship W1985654472A5003238248 @default.
• W1985654472 hasAuthorship W1985654472A5033389134 @default.
• W1985654472 hasAuthorship W1985654472A5058534161 @default.
• W1985654472 hasAuthorship W1985654472A5077250479 @default.
• W1985654472 hasAuthorship W1985654472A5077722727 @default.
• W1985654472 hasBestOaLocation W19856544721 @default.
• W1985654472 hasConcept C129987498 @default.
• W1985654472 hasConcept C141547260 @default.
• W1985654472 hasConcept C142724271 @default.
• W1985654472 hasConcept C169760540 @default.
• W1985654472 hasConcept C172497186 @default.
• W1985654472 hasConcept C197534660 @default.
• W1985654472 hasConcept C204787440 @default.
• W1985654472 hasConcept C2776164576 @default.
• W1985654472 hasConcept C2781347215 @default.
• W1985654472 hasConcept C3020332539 @default.
• W1985654472 hasConcept C71924100 @default.
• W1985654472 hasConcept C86803240 @default.
• W1985654472 hasConcept C94487597 @default.

• next