Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985671555> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1985671555 endingPage "128" @default.
- W1985671555 startingPage "125" @default.
- W1985671555 abstract "It has been shown previously that a single intravenous injection of mouse F, LNC into either parent results in a rapid reduction in the ability of the recipient to generate CTL reactive against donor antigens in an in vitro MLR. The underlying mechanism appears to be the in-activation of host CTL precursors that can recognize donor lymphocytes that have entered the recirculating pool. The donor lymphocytes may be acting as functionally deleting APC, or veto cells. Here, we have injected C57BL/6 (B6) mice with (C57BL/6×DBA/2) F1 (F1) LNC. The CTL response against donor LNC was maximally reduced by 2 days and stayed reduced for at least 6 weeks, but ultimately recovered to normal levels. The response reduction mechanism remained operative during the period when the response was reduced: Fresh FITC-labeled B6 LNC introduced into B6 recipients of an earlier injection of F1 LNC were as effectively deleted of F1-reactive CTLp as the original host B6 LNC population, the fresh FITC-labelled B6 LNC being separated from host B6 LNC by cell sorting before testing. When B6 mice injected with F1 LNC ultimately recovered their response against F1 donor antigens, reinjection of F1 LNC did not induce a new response reduction. Instead of entering the recirculating pool, the injected F1 cells were rapidly removed by a specific immune process." @default.
- W1985671555 created "2016-06-24" @default.
- W1985671555 creator A5016938805 @default.
- W1985671555 creator A5058083423 @default.
- W1985671555 creator A5072980336 @default.
- W1985671555 date "1992-07-01" @default.
- W1985671555 modified "2023-10-16" @default.
- W1985671555 title "RAPID AND LONG-TERM CHANGES TO HOST CYTOTOXIC T LYMPHOCYTE PRECURSORS REACTIVE TO DONOR ANTIGENS CAUSED BY INTRAVENOUS INJECTION OF HISTOINCOMPATIBLE LYMPHOCYTES" @default.
- W1985671555 doi "https://doi.org/10.1097/00007890-199207000-00022" @default.
- W1985671555 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1631921" @default.
- W1985671555 hasPublicationYear "1992" @default.
- W1985671555 type Work @default.
- W1985671555 sameAs 1985671555 @default.
- W1985671555 citedByCount "19" @default.
- W1985671555 crossrefType "journal-article" @default.
- W1985671555 hasAuthorship W1985671555A5016938805 @default.
- W1985671555 hasAuthorship W1985671555A5058083423 @default.
- W1985671555 hasAuthorship W1985671555A5072980336 @default.
- W1985671555 hasBestOaLocation W19856715551 @default.
- W1985671555 hasConcept C147483822 @default.
- W1985671555 hasConcept C147969180 @default.
- W1985671555 hasConcept C153911025 @default.
- W1985671555 hasConcept C154317977 @default.
- W1985671555 hasConcept C185592680 @default.
- W1985671555 hasConcept C202751555 @default.
- W1985671555 hasConcept C203014093 @default.
- W1985671555 hasConcept C2776090121 @default.
- W1985671555 hasConcept C2777761686 @default.
- W1985671555 hasConcept C2778740727 @default.
- W1985671555 hasConcept C2908647359 @default.
- W1985671555 hasConcept C2992881475 @default.
- W1985671555 hasConcept C55493867 @default.
- W1985671555 hasConcept C71924100 @default.
- W1985671555 hasConcept C86803240 @default.
- W1985671555 hasConcept C8891405 @default.
- W1985671555 hasConcept C99454951 @default.
- W1985671555 hasConceptScore W1985671555C147483822 @default.
- W1985671555 hasConceptScore W1985671555C147969180 @default.
- W1985671555 hasConceptScore W1985671555C153911025 @default.
- W1985671555 hasConceptScore W1985671555C154317977 @default.
- W1985671555 hasConceptScore W1985671555C185592680 @default.
- W1985671555 hasConceptScore W1985671555C202751555 @default.
- W1985671555 hasConceptScore W1985671555C203014093 @default.
- W1985671555 hasConceptScore W1985671555C2776090121 @default.
- W1985671555 hasConceptScore W1985671555C2777761686 @default.
- W1985671555 hasConceptScore W1985671555C2778740727 @default.
- W1985671555 hasConceptScore W1985671555C2908647359 @default.
- W1985671555 hasConceptScore W1985671555C2992881475 @default.
- W1985671555 hasConceptScore W1985671555C55493867 @default.
- W1985671555 hasConceptScore W1985671555C71924100 @default.
- W1985671555 hasConceptScore W1985671555C86803240 @default.
- W1985671555 hasConceptScore W1985671555C8891405 @default.
- W1985671555 hasConceptScore W1985671555C99454951 @default.
- W1985671555 hasIssue "1" @default.
- W1985671555 hasLocation W19856715551 @default.
- W1985671555 hasLocation W19856715552 @default.
- W1985671555 hasLocation W19856715553 @default.
- W1985671555 hasOpenAccess W1985671555 @default.
- W1985671555 hasPrimaryLocation W19856715551 @default.
- W1985671555 hasRelatedWork W141088424 @default.
- W1985671555 hasRelatedWork W1513096311 @default.
- W1985671555 hasRelatedWork W1965116372 @default.
- W1985671555 hasRelatedWork W2006542552 @default.
- W1985671555 hasRelatedWork W2006913667 @default.
- W1985671555 hasRelatedWork W2018916009 @default.
- W1985671555 hasRelatedWork W2026066486 @default.
- W1985671555 hasRelatedWork W2037807305 @default.
- W1985671555 hasRelatedWork W2050020144 @default.
- W1985671555 hasRelatedWork W2074023757 @default.
- W1985671555 hasVolume "54" @default.
- W1985671555 isParatext "false" @default.
- W1985671555 isRetracted "false" @default.
- W1985671555 magId "1985671555" @default.
- W1985671555 workType "article" @default.