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- W1985677415 abstract "<h3>Background and Aims</h3> Our aim was to determine the relationship between red blood cell transfusion and necrotizing enterocolitis (NEC) in all admitted very low birth weight (VLBW) infants with or without transfusion. <h3>Methods</h3> All VLBW neonates were categorized into five groups: subjects that developed NEC < 48 hours after transfusion (n = 15); subjects that developed NEC > 48 hours after transfusion (n = 31); subjects that were never transfused but developed NEC, (n = 50); subjects that were transfused but did not develop NEC, (n = 250); and subjects that were neither transfused nor developed NEC (n = 301). <h3>Results</h3> A group of 647 infants were enrolled in the study. Mean gestational age and birth weight of the patients were 29±3.1 weeks and 1157±237 grams, respectively. The mean age at the onset of NEC in the NEC groups were 20±2.3 days, 12±3 days, and 11±2.6 days, respectively (P<0.05). The mean interval from the last transfusion to the onset of NEC was 16.8±8.8 hours in Group 1 and 240±50 hours in Group 2 (p<0.05). <h3>Conclusion</h3> In this study, we sought to evaluate all VLBW infants, whether they received a transfusion or not. We suggest that transfusion associated NEC exists, but many other factors influence this multifactorial disease. The age of NEC onset was later in transfused versus non-transfused patients, whereas the interval between transfusion and NEC was shorter." @default.
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- W1985677415 date "2012-10-01" @default.
- W1985677415 modified "2023-09-30" @default.
- W1985677415 title "1379 Transfusion-Associated Necrotizing Enterocolitis in Very Low Birth Weight Premature Infants" @default.
- W1985677415 doi "https://doi.org/10.1136/archdischild-2012-302724.1379" @default.
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