FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985704237> ?p ?o ?g. }

• W1985704237 endingPage "31" @default.
• W1985704237 startingPage "1" @default.
• W1985704237 abstract "Functional, molecular and genetic neuroimaging has highlighted the existence of brain anomalies and neural vulnerability factors related to obesity and eating disorders such as binge eating or anorexia nervosa. In particular, decreased basal metabolism in the prefrontal cortex and striatum as well as dopaminergic alterations have been described in obese subjects, in parallel with increased activation of reward brain areas in response to palatable food cues. Elevated reward region responsivity may trigger food craving and predict future weight gain. This opens the way to prevention studies using functional and molecular neuroimaging to perform early diagnostics and to phenotype subjects at risk by exploring different neurobehavioral dimensions of the food choices and motivation processes. In the first part of this review, advantages and limitations of neuroimaging techniques, such as functional magnetic resonance imaging (fMRI), positron emission tomography (PET), single photon emission computed tomography (SPECT), pharmacogenetic fMRI and functional near-infrared spectroscopy (fNIRS) will be discussed in the context of recent work dealing with eating behavior, with a particular focus on obesity. In the second part of the review, non-invasive strategies to modulate food-related brain processes and functions will be presented. At the leading edge of non-invasive brain-based technologies is real-time fMRI (rtfMRI) neurofeedback, which is a powerful tool to better understand the complexity of human brain-behavior relationships. rtfMRI, alone or when combined with other techniques and tools such as EEG and cognitive therapy, could be used to alter neural plasticity and learned behavior to optimize and/or restore healthy cognition and eating behavior. Other promising non-invasive neuromodulation approaches being explored are repetitive transcranial magnetic stimulation (rTMS) and transcranial direct-current stimulation (tDCS). Converging evidence points at the value of these non-invasive neuromodulation strategies to study basic mechanisms underlying eating behavior and to treat its disorders. Both of these approaches will be compared in light of recent work in this field, while addressing technical and practical questions. The third part of this review will be dedicated to invasive neuromodulation strategies, such as vagus nerve stimulation (VNS) and deep brain stimulation (DBS). In combination with neuroimaging approaches, these techniques are promising experimental tools to unravel the intricate relationships between homeostatic and hedonic brain circuits. Their potential as additional therapeutic tools to combat pharmacorefractory morbid obesity or acute eating disorders will be discussed, in terms of technical challenges, applicability and ethics. In a general discussion, we will put the brain at the core of fundamental research, prevention and therapy in the context of obesity and eating disorders. First, we will discuss the possibility to identify new biological markers of brain functions. Second, we will highlight the potential of neuroimaging and neuromodulation in individualized medicine. Third, we will introduce the ethical questions that are concomitant to the emergence of new neuromodulation therapies." @default.
• W1985704237 created "2016-06-24" @default.
• W1985704237 creator A5002463971 @default.
• W1985704237 creator A5005290023 @default.
• W1985704237 creator A5020159141 @default.
• W1985704237 creator A5024467423 @default.
• W1985704237 creator A5031422040 @default.
• W1985704237 creator A5037016344 @default.
• W1985704237 creator A5046195753 @default.
• W1985704237 creator A5073619495 @default.
• W1985704237 creator A5078774752 @default.
• W1985704237 creator A5079365943 @default.
• W1985704237 date "2015-01-01" @default.
• W1985704237 modified "2023-10-15" @default.
• W1985704237 title "Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity" @default.
• W1985704237 cites W1482710307 @default.
• W1985704237 cites W1484259225 @default.
• W1985704237 cites W1485317826 @default.
• W1985704237 cites W1489516196 @default.
• W1985704237 cites W1542503752 @default.
• W1985704237 cites W1546113715 @default.
• W1985704237 cites W1549657738 @default.
• W1985704237 cites W1567226471 @default.
• W1985704237 cites W1580469578 @default.
• W1985704237 cites W1606110752 @default.
• W1985704237 cites W1639247225 @default.
• W1985704237 cites W1704561002 @default.
• W1985704237 cites W1779086192 @default.
• W1985704237 cites W1832133707 @default.
• W1985704237 cites W1845973883 @default.
• W1985704237 cites W1895520963 @default.
• W1985704237 cites W1902066760 @default.
• W1985704237 cites W1921511099 @default.
• W1985704237 cites W1954531422 @default.
• W1985704237 cites W1963534390 @default.
• W1985704237 cites W1964679987 @default.
• W1985704237 cites W1964821139 @default.
• W1985704237 cites W1964979617 @default.
• W1985704237 cites W1965119856 @default.
• W1985704237 cites W1965134469 @default.
• W1985704237 cites W1965412569 @default.
• W1985704237 cites W1965445933 @default.
• W1985704237 cites W1966010782 @default.
• W1985704237 cites W1967306986 @default.
• W1985704237 cites W1967830372 @default.
• W1985704237 cites W1968103681 @default.
• W1985704237 cites W1969231105 @default.
• W1985704237 cites W1972738529 @default.
• W1985704237 cites W1972879677 @default.
• W1985704237 cites W1974044266 @default.
• W1985704237 cites W1974091029 @default.
• W1985704237 cites W1974310475 @default.
• W1985704237 cites W1974695557 @default.
• W1985704237 cites W1975009247 @default.
• W1985704237 cites W1976438265 @default.
• W1985704237 cites W1976769729 @default.
• W1985704237 cites W1978277358 @default.
• W1985704237 cites W1979336020 @default.
• W1985704237 cites W1979565994 @default.
• W1985704237 cites W1980656169 @default.
• W1985704237 cites W1980882035 @default.
• W1985704237 cites W1981459575 @default.
• W1985704237 cites W1983229412 @default.
• W1985704237 cites W1983510054 @default.
• W1985704237 cites W1983896836 @default.
• W1985704237 cites W1984079790 @default.
• W1985704237 cites W1984208580 @default.
• W1985704237 cites W1985107350 @default.
• W1985704237 cites W1985400929 @default.
• W1985704237 cites W1986183494 @default.
• W1985704237 cites W1986223143 @default.
• W1985704237 cites W1986444907 @default.
• W1985704237 cites W1987593352 @default.
• W1985704237 cites W1987642408 @default.
• W1985704237 cites W1988338937 @default.
• W1985704237 cites W1988751658 @default.
• W1985704237 cites W1989423096 @default.
• W1985704237 cites W1990400194 @default.
• W1985704237 cites W1991330724 @default.
• W1985704237 cites W1995367461 @default.
• W1985704237 cites W1996175687 @default.
• W1985704237 cites W1996281935 @default.
• W1985704237 cites W1999822276 @default.
• W1985704237 cites W2000419993 @default.
• W1985704237 cites W2000844384 @default.
• W1985704237 cites W2001013654 @default.
• W1985704237 cites W2001085696 @default.
• W1985704237 cites W2001273564 @default.
• W1985704237 cites W2001430965 @default.
• W1985704237 cites W2002532911 @default.
• W1985704237 cites W2002904154 @default.
• W1985704237 cites W2003413351 @default.
• W1985704237 cites W2004004650 @default.
• W1985704237 cites W2004300026 @default.
• W1985704237 cites W2005341195 @default.
• W1985704237 cites W2006326305 @default.
• W1985704237 cites W2007687414 @default.
• W1985704237 cites W2007893377 @default.

• next