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- W1985715584 abstract "Abstract The frequency of occurrence of circular dimers, catenated dimers and higher oligomers has been determined in preparations of the covalently closed, circular DNA of the replicative form of the bacteriophage φX174. Fifty minutes after infection in the presence of chloramphenicol, 2.3, 1 and 0.3%, respectively, of the three types of molecules were present. The conditions for preparing the specimens for electron microscopy and the criteria for distinguishing circular and catenated dimers on micrographs have been formulated so that they can be uniformly applied in a survey of a large number of molecules. A similar survey of a gene IV mutant of bacteriophage S13, blocked in the replication of replicative form, was made. Circular dimers were present, although at a lower frequency than in wild type, indicating that their formation does not necessarily require replication. Catenanes were only slightly reduced in frequency." @default.
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- W1985715584 date "1970-02-01" @default.
- W1985715584 modified "2023-09-27" @default.
- W1985715584 title "Complex replicative form molecules of bacteriophages φX174 and S13 su105" @default.
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- W1985715584 doi "https://doi.org/10.1016/0022-2836(70)90317-7" @default.
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