Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985732336> ?p ?o ?g. }
- W1985732336 endingPage "120" @default.
- W1985732336 startingPage "107" @default.
- W1985732336 abstract "In signal transduction and other biological processes, molecular interaction plays an important role. Real-time data on molecular interactions can be helpful in understanding the relationship between occurrence of these processes and binding. Surface-plasmon resonance (SPR) sensors, which provide quantitative, real-time binding data, have evolved as useful tools in a broad range of applications. However, as the monitoring of an interaction between a protein or small molecular ligands and a receptor molecule provides no unambiguous information on the identity of the bound material due to lack of selectivity (e.g., cross reactivity) of the receptor molecule involved, a second technique is necessary for identification. Mass spectrometry (MS) is a suitable method and various MS techniques have been used in conjunction with affinity surfaces in recent years. This article gives an overview of the developments in SPR-MS. We describe the approaches and the technology for combining SPR interaction monitoring and identification of proteins and low-molecular-weight ligands using MS (i.e. on-chip SPR-MS and sample elution prior to MS analyses). We discuss developments in instrumentation, including sensor miniaturization and microfluidics." @default.
- W1985732336 created "2016-06-24" @default.
- W1985732336 creator A5017222673 @default.
- W1985732336 creator A5046661376 @default.
- W1985732336 creator A5085321329 @default.
- W1985732336 date "2013-04-01" @default.
- W1985732336 modified "2023-10-11" @default.
- W1985732336 title "Coupling surface-plasmon resonance and mass spectrometry to quantify and to identify ligands" @default.
- W1985732336 cites W170023867 @default.
- W1985732336 cites W1969265357 @default.
- W1985732336 cites W1973197717 @default.
- W1985732336 cites W1977972314 @default.
- W1985732336 cites W1980163175 @default.
- W1985732336 cites W1986547496 @default.
- W1985732336 cites W1986577983 @default.
- W1985732336 cites W1986939380 @default.
- W1985732336 cites W1996582799 @default.
- W1985732336 cites W1999789795 @default.
- W1985732336 cites W2001600761 @default.
- W1985732336 cites W2004077554 @default.
- W1985732336 cites W2005926648 @default.
- W1985732336 cites W2006069768 @default.
- W1985732336 cites W2016254471 @default.
- W1985732336 cites W2021928695 @default.
- W1985732336 cites W2024978079 @default.
- W1985732336 cites W2027100614 @default.
- W1985732336 cites W2030018233 @default.
- W1985732336 cites W2033096525 @default.
- W1985732336 cites W2034655114 @default.
- W1985732336 cites W2036638827 @default.
- W1985732336 cites W2037319814 @default.
- W1985732336 cites W2040677997 @default.
- W1985732336 cites W2056581388 @default.
- W1985732336 cites W2058770367 @default.
- W1985732336 cites W2061561975 @default.
- W1985732336 cites W2063611055 @default.
- W1985732336 cites W2065567795 @default.
- W1985732336 cites W2066358159 @default.
- W1985732336 cites W2067535176 @default.
- W1985732336 cites W2069490063 @default.
- W1985732336 cites W2071063588 @default.
- W1985732336 cites W2072982772 @default.
- W1985732336 cites W2075488228 @default.
- W1985732336 cites W2075580491 @default.
- W1985732336 cites W2075653938 @default.
- W1985732336 cites W2076251207 @default.
- W1985732336 cites W2077127768 @default.
- W1985732336 cites W2077538125 @default.
- W1985732336 cites W2078914987 @default.
- W1985732336 cites W2080179575 @default.
- W1985732336 cites W2080699856 @default.
- W1985732336 cites W2081938042 @default.
- W1985732336 cites W2083646002 @default.
- W1985732336 cites W2085597996 @default.
- W1985732336 cites W2087117264 @default.
- W1985732336 cites W2088224373 @default.
- W1985732336 cites W2094119867 @default.
- W1985732336 cites W2116040802 @default.
- W1985732336 cites W2116909762 @default.
- W1985732336 cites W2119785984 @default.
- W1985732336 cites W2121335806 @default.
- W1985732336 cites W2126792758 @default.
- W1985732336 cites W2135413594 @default.
- W1985732336 cites W2136725438 @default.
- W1985732336 cites W2167350333 @default.
- W1985732336 cites W2168387967 @default.
- W1985732336 cites W2322237012 @default.
- W1985732336 doi "https://doi.org/10.1016/j.trac.2012.09.004" @default.
- W1985732336 hasPublicationYear "2013" @default.
- W1985732336 type Work @default.
- W1985732336 sameAs 1985732336 @default.
- W1985732336 citedByCount "20" @default.
- W1985732336 countsByYear W19857323362013 @default.
- W1985732336 countsByYear W19857323362014 @default.
- W1985732336 countsByYear W19857323362015 @default.
- W1985732336 countsByYear W19857323362016 @default.
- W1985732336 countsByYear W19857323362017 @default.
- W1985732336 countsByYear W19857323362019 @default.
- W1985732336 countsByYear W19857323362020 @default.
- W1985732336 countsByYear W19857323362021 @default.
- W1985732336 countsByYear W19857323362022 @default.
- W1985732336 countsByYear W19857323362023 @default.
- W1985732336 crossrefType "journal-article" @default.
- W1985732336 hasAuthorship W1985732336A5017222673 @default.
- W1985732336 hasAuthorship W1985732336A5046661376 @default.
- W1985732336 hasAuthorship W1985732336A5085321329 @default.
- W1985732336 hasConcept C10390740 @default.
- W1985732336 hasConcept C106847996 @default.
- W1985732336 hasConcept C113196181 @default.
- W1985732336 hasConcept C155672457 @default.
- W1985732336 hasConcept C161624437 @default.
- W1985732336 hasConcept C162356407 @default.
- W1985732336 hasConcept C171250308 @default.
- W1985732336 hasConcept C178790620 @default.
- W1985732336 hasConcept C179303850 @default.
- W1985732336 hasConcept C185592680 @default.
- W1985732336 hasConcept C186060115 @default.
- W1985732336 hasConcept C192562407 @default.