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- W1985758426 endingPage "717" @default.
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- W1985758426 abstract "Members of the nuclear receptor gene family act as biological rheostats to maintain metabolic homeostasis in response to endocrine and nutritional changes. The liver X (LXR) and thyroid hormone (TR) receptors have been shown to regulate overlapping but distinct metabolic pathways important for overall lipid homeostasis. Dyslipidemia is one out of four key determinants for cardiovascular risk and both LXRs and TRs may provide attractive targets for intervention of cardiovascular disease. In this review we will compare the two receptor systems to highlight similarities and differences in structure and function with implications for development of novel treatments for dyslipidemia and atherosclerosis." @default.
- W1985758426 created "2016-06-24" @default.
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- W1985758426 creator A5071823141 @default.
- W1985758426 date "2004-10-01" @default.
- W1985758426 modified "2023-10-03" @default.
- W1985758426 title "Convergence of lipid homeostasis through liver X and thyroid hormone receptors" @default.
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- W1985758426 doi "https://doi.org/10.1016/j.mad.2004.05.005" @default.
- W1985758426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15541766" @default.
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