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- W1985777645 abstract "There have been several reports that Mg++-activated ATPase is present in the catecholamine storage granules of the adrenal medulla (1-3) and that this ATPase may be linked in some way with the ATP-Mg++ stimulated uptake and release of catecholamine by isolated granules (4-9). Recently, we found that the low concentration of Ca++ present in the incubation medium as a contaminant participated in the release of catecholamine from the granules stimulated by ATP and Mg++ (10). This finding is interesting in relation to the fact that acetylcholine or excess potassium causes the release of catecholamine from a perfused adrenal gland by promoting increased uptake of Ca++ into the cells (11-13). This paper reports investigations on the effect of Ca++ on the Mg++-activated ATPase activity in isolated catecholamine storage granules from the adrenal medulla. The possible relationship of these results to the release of catecholamine from the granules is discussed." @default.
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- W1985777645 date "1971-01-01" @default.
- W1985777645 modified "2023-09-23" @default.
- W1985777645 title "ROLE OF CALCIUM FOR MAGNESIUM-ACTIVATED ADENOSINETRIPHOSPHATASE ACTIVITY AND ADENOSINETRIPHOSPHATE-MAGNESIUM STIMULATED CATECHOLAMINE RELEASE FROM ADRENAL MEDULLARY GRANULES" @default.
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- W1985777645 doi "https://doi.org/10.1254/jjp.21.739" @default.
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