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- W1985798349 abstract "The syntheses and in vitro evaluation of a new series of pyrido[2,3-d]pyrimidine-2,4-diones bearing substituents at C-3 and/or C-4 positions on the pyridine ring are described. Some of these compounds, especially 51 and 6f, were found to be potent phosphodiesterase 4 (PDE 4) inhibitors exhibiting improved ratio of PDE 4 inhibitory activity:rolipram binding assay (RBA)." @default.
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- W1985798349 date "2001-03-01" @default.
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- W1985798349 title "Syntheses and evaluation of pyrido[2,3-d]pyrimidine-2,4-diones as PDE 4 inhibitors" @default.
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- W1985798349 doi "https://doi.org/10.1016/s0960-894x(00)00681-8" @default.
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