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- W1985807712 abstract "Purpose: To determine a valid and practical routine for glomerular filtration rate measurement in gynaecologic cancer patients. Material and Methods: The established method, endogenous creatinine clearance, was compared to 51 Cr-EDTA clearance and contrast medium clearance in 68 women with various gynaecologic carcinomas. Contrast medium clearance was determined in association with conventional urography (iohexol 300 mg I/ml, 40 ml) for evaluation of urinary tract involvement by the tumour. Automated X-ray fluorescence analysis equipment was used for the plasma analysis of iohexol and clearance calculations. Endogenous creatinine clearance and 51 Cr-EDTA clearance were determined according to standard routine procedures. Simultaneous determinations of contrast medium clearance and 51 Cr-EDTA clearance (n=33), contrast medium clearance and endogenous creatinine clearance (n=50), as well as 51 Cr-EDTA clearance and endogenous creatinine clearance (n=30) were compared. Results and Conclusion: The mean differences were −2.8 (SD 6.6), −1.8 (SD 22.3), and 2.7 (SD 18.3) ml/min/1.73 m 2 , respectively. It is concluded that contrast medium clearance is as adequate as 51 Cr-EDTA clearance for glomerular filtration rate measurement. We suggest that contrast medium clearance should replace endogenous creatinine clearance, especially in patients referred for urography." @default.
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- W1985807712 date "1996-05-01" @default.
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- W1985807712 title "Iohexol Clearance for Renal Function Measurement in Gynaecologic Cancer Patients" @default.
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- W1985807712 doi "https://doi.org/10.1177/02841851960373p231" @default.
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