FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985842890> ?p ?o ?g. }

• W1985842890 endingPage "673.e2" @default.
• W1985842890 startingPage "666" @default.
• W1985842890 abstract "There is increasing evidence that suggests that particular histopathologic types of non-small-cell lung cancer (NSCLC) display distinct molecular characteristics. We analyzed, in lung squamous cell carcinoma (SCC) and adenocarcinoma (AC), the expression of 8 genes that constitute 2 previously reported prognostic expression signatures in NSCLC.Fresh-frozen tumor and normal lung samples were obtained at surgery from 135 patients with stage I-III NSCLC (89 (65.9%) SCC, 46 (34.1%) AC). Expression of CSF1 (colony stimulating factor for macrophages), carbonic anhydrase 9 (CA9), epithelial growth factor receptor (EGFR), dual specificity phosphatase 6 (DUSP6), v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (ERBB3), monocyte to macrophage differentiation-associated (MMD), lymphocyte-specific protein tyrosine kinase (LCK) and signal transducer and activator of transcription 1 (STAT1) was assessed in SCC, AC, and in normal lung by quantitative reverse transcriptase - polymerase chain reaction (qRT-PCR). Metastasis-free survival was analyzed according to the median value of gene expression in the entire NSCLC cohort and separately in SCC and AC.Expression of CA9, CSF1, DUSP6, STAT1, and MMD differed between NSCLC and normal lung. EGFR was more abundant in SCC compared with AC, whereas the reverse was true for DUSP6 and ERBB3. A high expression of CSF1 correlated with shorter metastasis-free survival in the entire NSCLC group (P = .016) and in SCC (P = .049) and AC (P = .034) cohorts.Several genes considered prognostic in NSCLC showed significantly different expression in SCC and AC, and thus should be analyzed separately in these 2 subtypes for their prognostic significance. CSF1 is similarly expressed in SCC and AC, and portends a poor outcome in the entire group of patients with NSCLC, and in SCC and AC when considered separately." @default.
• W1985842890 created "2016-06-24" @default.
• W1985842890 creator A5004874011 @default.
• W1985842890 creator A5005308261 @default.
• W1985842890 creator A5008897387 @default.
• W1985842890 creator A5014322331 @default.
• W1985842890 creator A5016911330 @default.
• W1985842890 creator A5017484722 @default.
• W1985842890 creator A5030827550 @default.
• W1985842890 creator A5044887899 @default.
• W1985842890 creator A5052637796 @default.
• W1985842890 creator A5066844095 @default.
• W1985842890 creator A5067054501 @default.
• W1985842890 creator A5067792919 @default.
• W1985842890 creator A5091656031 @default.
• W1985842890 date "2013-11-01" @default.
• W1985842890 modified "2023-10-16" @default.
• W1985842890 title "Main Histologic Types of Non–Small-Cell Lung Cancer Differ in Expression of Prognosis-related Genes" @default.
• W1985842890 cites W1577577364 @default.
• W1985842890 cites W1969994476 @default.
• W1985842890 cites W1970439470 @default.
• W1985842890 cites W1985329793 @default.
• W1985842890 cites W1998016276 @default.
• W1985842890 cites W2000217512 @default.
• W1985842890 cites W2000582156 @default.
• W1985842890 cites W2009398566 @default.
• W1985842890 cites W2010225305 @default.
• W1985842890 cites W2032689481 @default.
• W1985842890 cites W2032947646 @default.
• W1985842890 cites W2037489902 @default.
• W1985842890 cites W2040839214 @default.
• W1985842890 cites W2044152222 @default.
• W1985842890 cites W2055748108 @default.
• W1985842890 cites W2070544303 @default.
• W1985842890 cites W2083851586 @default.
• W1985842890 cites W2084001490 @default.
• W1985842890 cites W2084411099 @default.
• W1985842890 cites W2093007798 @default.
• W1985842890 cites W2095226995 @default.
• W1985842890 cites W2095618958 @default.
• W1985842890 cites W2096984065 @default.
• W1985842890 cites W2097413644 @default.
• W1985842890 cites W2101326169 @default.
• W1985842890 cites W2104504726 @default.
• W1985842890 cites W2107277218 @default.
• W1985842890 cites W2114060414 @default.
• W1985842890 cites W2114348576 @default.
• W1985842890 cites W2115157373 @default.
• W1985842890 cites W2116088571 @default.
• W1985842890 cites W2118833050 @default.
• W1985842890 cites W2132165198 @default.
• W1985842890 cites W2133585947 @default.
• W1985842890 cites W2142351815 @default.
• W1985842890 cites W2148539553 @default.
• W1985842890 cites W2150688669 @default.
• W1985842890 cites W2154254051 @default.
• W1985842890 cites W2154576630 @default.
• W1985842890 cites W2156728903 @default.
• W1985842890 cites W2157485001 @default.
• W1985842890 cites W2158086631 @default.
• W1985842890 cites W2167165074 @default.
• W1985842890 cites W70819804 @default.
• W1985842890 doi "https://doi.org/10.1016/j.cllc.2013.04.010" @default.
• W1985842890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23870818" @default.
• W1985842890 hasPublicationYear "2013" @default.
• W1985842890 type Work @default.
• W1985842890 sameAs 1985842890 @default.
• W1985842890 citedByCount "34" @default.
• W1985842890 countsByYear W19858428902013 @default.
• W1985842890 countsByYear W19858428902014 @default.
• W1985842890 countsByYear W19858428902015 @default.
• W1985842890 countsByYear W19858428902016 @default.
• W1985842890 countsByYear W19858428902017 @default.
• W1985842890 countsByYear W19858428902018 @default.
• W1985842890 countsByYear W19858428902019 @default.
• W1985842890 countsByYear W19858428902020 @default.
• W1985842890 countsByYear W19858428902021 @default.
• W1985842890 countsByYear W19858428902022 @default.
• W1985842890 countsByYear W19858428902023 @default.
• W1985842890 crossrefType "journal-article" @default.
• W1985842890 hasAuthorship W1985842890A5004874011 @default.
• W1985842890 hasAuthorship W1985842890A5005308261 @default.
• W1985842890 hasAuthorship W1985842890A5008897387 @default.
• W1985842890 hasAuthorship W1985842890A5014322331 @default.
• W1985842890 hasAuthorship W1985842890A5016911330 @default.
• W1985842890 hasAuthorship W1985842890A5017484722 @default.
• W1985842890 hasAuthorship W1985842890A5030827550 @default.
• W1985842890 hasAuthorship W1985842890A5044887899 @default.
• W1985842890 hasAuthorship W1985842890A5052637796 @default.
• W1985842890 hasAuthorship W1985842890A5066844095 @default.
• W1985842890 hasAuthorship W1985842890A5067054501 @default.
• W1985842890 hasAuthorship W1985842890A5067792919 @default.
• W1985842890 hasAuthorship W1985842890A5091656031 @default.
• W1985842890 hasConcept C121608353 @default.
• W1985842890 hasConcept C126322002 @default.
• W1985842890 hasConcept C142724271 @default.
• W1985842890 hasConcept C2776256026 @default.
• W1985842890 hasConcept C2781182431 @default.

• next