Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985873358> ?p ?o ?g. }
- W1985873358 endingPage "147" @default.
- W1985873358 startingPage "141" @default.
- W1985873358 abstract "ABSTRACT: Nonsteroidal anti‐inflammatory drugs (NSAIDs) gained popularity in the late 1970s. Inhibition of prostaglandin synthesis with indomethacin has been reported to be effective for prevention of labor and for treatment for symptomatic polyhydramnios. Concern about its possible constrictive effect on the fetal ductus arteriosus has limited its use in pregnancy. Maternal indomethacin therapy has also been associated with reduction in urine production in the fetus and with oligohydramnios. Obstetricians have discouraged pregnant women from taking analgesic doses of aspirin, mainly because of the availability of paracetamol (acetaminophen), which causes less gastric irritation, but also because of fear of maternal and fetal hemorrhage and of possible premature closure of the ductus. These fears largely derive from studies on patients taking large doses and from extrapolation from other NSAIDs. The likelihood that treatment with 60–75 mg/day of aspirin markedly reduces the incidence of preeclampsia and fetal intrauterine growth retardation makes it important to reexamine its use. This review describes the pharmacology and pharmacokinetics of aspirin with particular reference to pregnancy and considers teratogenesis, prolongation of pregnancy and labor, maternal bleeding, fetal and neonatal bleeding, possible effects on the ductus arteriosus and pulmonary circulation, and possible nonspecific effects on intelligence and breast feeding and acute toxicity in the neonate." @default.
- W1985873358 created "2016-06-24" @default.
- W1985873358 creator A5010389684 @default.
- W1985873358 creator A5031467053 @default.
- W1985873358 creator A5047981729 @default.
- W1985873358 creator A5057880429 @default.
- W1985873358 date "1992-10-12" @default.
- W1985873358 modified "2023-10-12" @default.
- W1985873358 title "NSAIDs: Maternal and Fetal Considerations" @default.
- W1985873358 cites W1427808478 @default.
- W1985873358 cites W1491093697 @default.
- W1985873358 cites W1491528029 @default.
- W1985873358 cites W1506467134 @default.
- W1985873358 cites W1508637117 @default.
- W1985873358 cites W1514580829 @default.
- W1985873358 cites W1530042784 @default.
- W1985873358 cites W182830905 @default.
- W1985873358 cites W1898546811 @default.
- W1985873358 cites W1964032360 @default.
- W1985873358 cites W1965884415 @default.
- W1985873358 cites W1968922054 @default.
- W1985873358 cites W1971369154 @default.
- W1985873358 cites W1972453460 @default.
- W1985873358 cites W1972901922 @default.
- W1985873358 cites W1974546287 @default.
- W1985873358 cites W1975152803 @default.
- W1985873358 cites W1981500616 @default.
- W1985873358 cites W1984056202 @default.
- W1985873358 cites W1984379075 @default.
- W1985873358 cites W1985001641 @default.
- W1985873358 cites W1986556515 @default.
- W1985873358 cites W1989521018 @default.
- W1985873358 cites W1989987972 @default.
- W1985873358 cites W1990394299 @default.
- W1985873358 cites W1993604342 @default.
- W1985873358 cites W1995487592 @default.
- W1985873358 cites W1997100253 @default.
- W1985873358 cites W1998728187 @default.
- W1985873358 cites W1999137813 @default.
- W1985873358 cites W2003408726 @default.
- W1985873358 cites W2003543090 @default.
- W1985873358 cites W2003912769 @default.
- W1985873358 cites W2004073841 @default.
- W1985873358 cites W2011512848 @default.
- W1985873358 cites W2017717455 @default.
- W1985873358 cites W2020341395 @default.
- W1985873358 cites W2022461235 @default.
- W1985873358 cites W2024249186 @default.
- W1985873358 cites W2024480243 @default.
- W1985873358 cites W2025319642 @default.
- W1985873358 cites W2026433108 @default.
- W1985873358 cites W2027783805 @default.
- W1985873358 cites W2029520243 @default.
- W1985873358 cites W2031836043 @default.
- W1985873358 cites W2036728575 @default.
- W1985873358 cites W2040406603 @default.
- W1985873358 cites W2042000315 @default.
- W1985873358 cites W2047455260 @default.
- W1985873358 cites W2048260363 @default.
- W1985873358 cites W2049556573 @default.
- W1985873358 cites W2049653456 @default.
- W1985873358 cites W2050476405 @default.
- W1985873358 cites W2050995483 @default.
- W1985873358 cites W2051092599 @default.
- W1985873358 cites W2054252710 @default.
- W1985873358 cites W2055770709 @default.
- W1985873358 cites W2056553795 @default.
- W1985873358 cites W2058043798 @default.
- W1985873358 cites W2064426727 @default.
- W1985873358 cites W2065030639 @default.
- W1985873358 cites W2067590826 @default.
- W1985873358 cites W2067991002 @default.
- W1985873358 cites W2069469117 @default.
- W1985873358 cites W2069499730 @default.
- W1985873358 cites W2070051550 @default.
- W1985873358 cites W2070828854 @default.
- W1985873358 cites W2071018066 @default.
- W1985873358 cites W2071733947 @default.
- W1985873358 cites W2074305211 @default.
- W1985873358 cites W2074387707 @default.
- W1985873358 cites W2077149488 @default.
- W1985873358 cites W2078801371 @default.
- W1985873358 cites W2080069662 @default.
- W1985873358 cites W2082256670 @default.
- W1985873358 cites W2087405635 @default.
- W1985873358 cites W2088347961 @default.
- W1985873358 cites W2088606646 @default.
- W1985873358 cites W2089076671 @default.
- W1985873358 cites W2091755086 @default.
- W1985873358 cites W2092473891 @default.
- W1985873358 cites W2099347055 @default.
- W1985873358 cites W2111621002 @default.
- W1985873358 cites W2124078483 @default.
- W1985873358 cites W2129105336 @default.
- W1985873358 cites W2140029871 @default.
- W1985873358 cites W2145107463 @default.
- W1985873358 cites W2150922552 @default.
- W1985873358 cites W2158014017 @default.