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• W1985907029 abstract "The labeling of a monoclonal (anti-CEA) and a polyclonal (IgG) antibody with 153Sm has been investigated, using the bicyclic anhydride of DTPA (cDTPAa) as the chelating agent. The radiochemical study was performed using a combination of radioanalytical techniques (gel filtration, HPLC, ITLC-SG and SDS-PAGE). Optimization of factors affecting labeling (pH, Ab, Ab-DTPA concentration, etc.) leads to a labeling yield higher than 90%. Biodistribution studies in normal mice showed slow blood clearance and high uptake into the liver, kidney and lungs." @default.
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• W1985907029 date "2002-11-01" @default.
• W1985907029 modified "2023-10-05" @default.
• W1985907029 title "Labeling of monoclonal antibodies with 153Sm for potential use in radioimmunotherapy" @default.
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• W1985907029 doi "https://doi.org/10.1016/s0969-8043(02)00181-1" @default.
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