Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985945410> ?p ?o ?g. }
- W1985945410 endingPage "1544" @default.
- W1985945410 startingPage "1539" @default.
- W1985945410 abstract "Water-soluble extracellular polysaccharides are known to possess weak or no in vitro antitumor activity. In this experiment, a mixture of extracellular Ganoderma lucidum polysaccharides (GLP) from the submerged fermentation broth was sulfated and studied on their antitumor activity. The sulfated GLP performed significant inhibition on the proliferation of assayed carcinoma cells in a dose-dependent manner, and present a degree of substitution-dependent suppressing to HepG2 cells. Meanwhile, the sulfated GLP presented remarkable but not dose-dependent inhibition on Heps hepatona in mice. With same degree of substitution, the sulfation protocol with aminosulfonic acid–pyridine yielded GLP sulfates with higher activity on HepG2 cells. In comparison, the native GLP showed no or little antitumor activity on the assayed cell lines but remarkable inhibition on suppressing the proliferation of rat Heps. The highest in vivo inhibition rate of 55.5% provided by sulfated GLP was observed on suppressing the proliferation of rat Heps." @default.
- W1985945410 created "2016-06-24" @default.
- W1985945410 creator A5018982005 @default.
- W1985945410 creator A5023702304 @default.
- W1985945410 creator A5028092806 @default.
- W1985945410 creator A5058555777 @default.
- W1985945410 creator A5075090550 @default.
- W1985945410 date "2012-01-01" @default.
- W1985945410 modified "2023-09-24" @default.
- W1985945410 title "Antitumor activity of sulfated extracellular polysaccharides of Ganoderma lucidum from the submerged fermentation broth" @default.
- W1985945410 cites W1972669317 @default.
- W1985945410 cites W1974298094 @default.
- W1985945410 cites W1975896225 @default.
- W1985945410 cites W1979291083 @default.
- W1985945410 cites W1985489730 @default.
- W1985945410 cites W1989882842 @default.
- W1985945410 cites W2003978030 @default.
- W1985945410 cites W2009400904 @default.
- W1985945410 cites W2019457053 @default.
- W1985945410 cites W2048897208 @default.
- W1985945410 cites W2050607195 @default.
- W1985945410 cites W2058716577 @default.
- W1985945410 cites W2067651150 @default.
- W1985945410 doi "https://doi.org/10.1016/j.carbpol.2011.09.051" @default.
- W1985945410 hasPublicationYear "2012" @default.
- W1985945410 type Work @default.
- W1985945410 sameAs 1985945410 @default.
- W1985945410 citedByCount "52" @default.
- W1985945410 countsByYear W19859454102012 @default.
- W1985945410 countsByYear W19859454102013 @default.
- W1985945410 countsByYear W19859454102014 @default.
- W1985945410 countsByYear W19859454102015 @default.
- W1985945410 countsByYear W19859454102016 @default.
- W1985945410 countsByYear W19859454102017 @default.
- W1985945410 countsByYear W19859454102018 @default.
- W1985945410 countsByYear W19859454102019 @default.
- W1985945410 countsByYear W19859454102020 @default.
- W1985945410 countsByYear W19859454102021 @default.
- W1985945410 countsByYear W19859454102022 @default.
- W1985945410 countsByYear W19859454102023 @default.
- W1985945410 crossrefType "journal-article" @default.
- W1985945410 hasAuthorship W1985945410A5018982005 @default.
- W1985945410 hasAuthorship W1985945410A5023702304 @default.
- W1985945410 hasAuthorship W1985945410A5028092806 @default.
- W1985945410 hasAuthorship W1985945410A5058555777 @default.
- W1985945410 hasAuthorship W1985945410A5075090550 @default.
- W1985945410 hasConcept C100544194 @default.
- W1985945410 hasConcept C100817775 @default.
- W1985945410 hasConcept C116073593 @default.
- W1985945410 hasConcept C150903083 @default.
- W1985945410 hasConcept C155138218 @default.
- W1985945410 hasConcept C185592680 @default.
- W1985945410 hasConcept C202751555 @default.
- W1985945410 hasConcept C207001950 @default.
- W1985945410 hasConcept C2776618520 @default.
- W1985945410 hasConcept C2779707156 @default.
- W1985945410 hasConcept C28406088 @default.
- W1985945410 hasConcept C2992468417 @default.
- W1985945410 hasConcept C2994085863 @default.
- W1985945410 hasConcept C31903555 @default.
- W1985945410 hasConcept C54355233 @default.
- W1985945410 hasConcept C55493867 @default.
- W1985945410 hasConcept C62112901 @default.
- W1985945410 hasConcept C81885089 @default.
- W1985945410 hasConcept C86803240 @default.
- W1985945410 hasConceptScore W1985945410C100544194 @default.
- W1985945410 hasConceptScore W1985945410C100817775 @default.
- W1985945410 hasConceptScore W1985945410C116073593 @default.
- W1985945410 hasConceptScore W1985945410C150903083 @default.
- W1985945410 hasConceptScore W1985945410C155138218 @default.
- W1985945410 hasConceptScore W1985945410C185592680 @default.
- W1985945410 hasConceptScore W1985945410C202751555 @default.
- W1985945410 hasConceptScore W1985945410C207001950 @default.
- W1985945410 hasConceptScore W1985945410C2776618520 @default.
- W1985945410 hasConceptScore W1985945410C2779707156 @default.
- W1985945410 hasConceptScore W1985945410C28406088 @default.
- W1985945410 hasConceptScore W1985945410C2992468417 @default.
- W1985945410 hasConceptScore W1985945410C2994085863 @default.
- W1985945410 hasConceptScore W1985945410C31903555 @default.
- W1985945410 hasConceptScore W1985945410C54355233 @default.
- W1985945410 hasConceptScore W1985945410C55493867 @default.
- W1985945410 hasConceptScore W1985945410C62112901 @default.
- W1985945410 hasConceptScore W1985945410C81885089 @default.
- W1985945410 hasConceptScore W1985945410C86803240 @default.
- W1985945410 hasFunder F4320321001 @default.
- W1985945410 hasIssue "2" @default.
- W1985945410 hasLocation W19859454101 @default.
- W1985945410 hasOpenAccess W1985945410 @default.
- W1985945410 hasPrimaryLocation W19859454101 @default.
- W1985945410 hasRelatedWork W2078509101 @default.
- W1985945410 hasRelatedWork W2172170558 @default.
- W1985945410 hasRelatedWork W2363576145 @default.
- W1985945410 hasRelatedWork W2364008860 @default.
- W1985945410 hasRelatedWork W2371957398 @default.
- W1985945410 hasRelatedWork W2382173880 @default.
- W1985945410 hasRelatedWork W2383405247 @default.
- W1985945410 hasRelatedWork W2384493127 @default.
- W1985945410 hasRelatedWork W2387062417 @default.