FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985953495> ?p ?o ?g. }

• W1985953495 endingPage "262" @default.
• W1985953495 startingPage "252" @default.
• W1985953495 abstract "The synthesis of citrate synthase (citrate oxaloacetate-lyase (CoA-acetylating), EC 4.1.3.7) from Bacillus subtilis was found to respond to a dual control: A specific feedback repression caused by glutamate (or α-ketoglutarate), the biosynthetic end product of the first half of the tricarboxylic acid cycle, and a more general catabolite repression resulting from the accumulation of catabolic intermediates when cells were grown on glucose, a readily utilizable carbon source. The synthesis of aconitate hydratase (citrate (isocitrate) hydro-lyase, EC 4.2.1.3, formerly known as aconitase) from this organism is sensitive to similar metabolic signals1. Because the kinetic patterns of repression and depression of the two enzymes are similar, and since a plot of the specific activities of aconitate hydratase vs. those of citrate synthase from B. subtilis cultures grown under differing nutritional conditions results in a straight line, the suggestion is made that citrate synthase and aconitate hydratase may be subject to coordinate regulation. Kinetic studies on a partially purified enzyme preparation show ATP to be an inhibitor of citrate synthase. ATP inhibition is competitive with CoASAc but not oxaloacetate. The results of this investigation lead to the conclusion that while the synthesis of citrate synthase is sensitive to both anabolic and catabolic signals, once the enzyme is formed, its activity is regulated primarily by catabolic effectors." @default.
• W1985953495 created "2016-06-24" @default.
• W1985953495 creator A5031299477 @default.
• W1985953495 creator A5058599722 @default.
• W1985953495 date "1969-07-01" @default.
• W1985953495 modified "2023-09-26" @default.
• W1985953495 title "Coarse and fine control of citrate synthase from Bacillus subtilis" @default.
• W1985953495 cites W1491211844 @default.
• W1985953495 cites W1550930759 @default.
• W1985953495 cites W1561356315 @default.
• W1985953495 cites W1571491229 @default.
• W1985953495 cites W1572024157 @default.
• W1985953495 cites W1591226471 @default.
• W1985953495 cites W1678194650 @default.
• W1985953495 cites W1775749144 @default.
• W1985953495 cites W1800127113 @default.
• W1985953495 cites W1980750579 @default.
• W1985953495 cites W1984313433 @default.
• W1985953495 cites W1986764507 @default.
• W1985953495 cites W2024486738 @default.
• W1985953495 cites W2029555482 @default.
• W1985953495 cites W2045580133 @default.
• W1985953495 cites W2046910983 @default.
• W1985953495 cites W2060282276 @default.
• W1985953495 cites W2063644507 @default.
• W1985953495 cites W2068347019 @default.
• W1985953495 cites W2082520757 @default.
• W1985953495 cites W2108933432 @default.
• W1985953495 cites W2125531893 @default.
• W1985953495 cites W2135984258 @default.
• W1985953495 cites W2276101456 @default.
• W1985953495 cites W2276809641 @default.
• W1985953495 cites W2288814114 @default.
• W1985953495 doi "https://doi.org/10.1016/0304-4165(69)90027-0" @default.
• W1985953495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4980242" @default.
• W1985953495 hasPublicationYear "1969" @default.
• W1985953495 type Work @default.
• W1985953495 sameAs 1985953495 @default.
• W1985953495 citedByCount "60" @default.
• W1985953495 countsByYear W19859534952014 @default.
• W1985953495 countsByYear W19859534952020 @default.
• W1985953495 countsByYear W19859534952022 @default.
• W1985953495 countsByYear W19859534952023 @default.
• W1985953495 crossrefType "journal-article" @default.
• W1985953495 hasAuthorship W1985953495A5031299477 @default.
• W1985953495 hasAuthorship W1985953495A5058599722 @default.
• W1985953495 hasConcept C104317684 @default.
• W1985953495 hasConcept C111133373 @default.
• W1985953495 hasConcept C112243037 @default.
• W1985953495 hasConcept C143065580 @default.
• W1985953495 hasConcept C165135838 @default.
• W1985953495 hasConcept C165267168 @default.
• W1985953495 hasConcept C181199279 @default.
• W1985953495 hasConcept C185592680 @default.
• W1985953495 hasConcept C200886947 @default.
• W1985953495 hasConcept C204999636 @default.
• W1985953495 hasConcept C2776336597 @default.
• W1985953495 hasConcept C2777269803 @default.
• W1985953495 hasConcept C2777272437 @default.
• W1985953495 hasConcept C2778470496 @default.
• W1985953495 hasConcept C523546767 @default.
• W1985953495 hasConcept C54355233 @default.
• W1985953495 hasConcept C55493867 @default.
• W1985953495 hasConcept C83941689 @default.
• W1985953495 hasConcept C86803240 @default.
• W1985953495 hasConcept C96942376 @default.
• W1985953495 hasConceptScore W1985953495C104317684 @default.
• W1985953495 hasConceptScore W1985953495C111133373 @default.
• W1985953495 hasConceptScore W1985953495C112243037 @default.
• W1985953495 hasConceptScore W1985953495C143065580 @default.
• W1985953495 hasConceptScore W1985953495C165135838 @default.
• W1985953495 hasConceptScore W1985953495C165267168 @default.
• W1985953495 hasConceptScore W1985953495C181199279 @default.
• W1985953495 hasConceptScore W1985953495C185592680 @default.
• W1985953495 hasConceptScore W1985953495C200886947 @default.
• W1985953495 hasConceptScore W1985953495C204999636 @default.
• W1985953495 hasConceptScore W1985953495C2776336597 @default.
• W1985953495 hasConceptScore W1985953495C2777269803 @default.
• W1985953495 hasConceptScore W1985953495C2777272437 @default.
• W1985953495 hasConceptScore W1985953495C2778470496 @default.
• W1985953495 hasConceptScore W1985953495C523546767 @default.
• W1985953495 hasConceptScore W1985953495C54355233 @default.
• W1985953495 hasConceptScore W1985953495C55493867 @default.
• W1985953495 hasConceptScore W1985953495C83941689 @default.
• W1985953495 hasConceptScore W1985953495C86803240 @default.
• W1985953495 hasConceptScore W1985953495C96942376 @default.
• W1985953495 hasIssue "2" @default.
• W1985953495 hasLocation W19859534951 @default.
• W1985953495 hasLocation W19859534952 @default.
• W1985953495 hasOpenAccess W1985953495 @default.
• W1985953495 hasPrimaryLocation W19859534951 @default.
• W1985953495 hasRelatedWork W1517649168 @default.
• W1985953495 hasRelatedWork W1549250878 @default.
• W1985953495 hasRelatedWork W1677117162 @default.
• W1985953495 hasRelatedWork W1985519997 @default.
• W1985953495 hasRelatedWork W2054369594 @default.
• W1985953495 hasRelatedWork W2171579454 @default.
• W1985953495 hasRelatedWork W2335291859 @default.

• next