Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985958315> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1985958315 endingPage "1703" @default.
- W1985958315 startingPage "1700" @default.
- W1985958315 abstract "Iatrogenic immunosuppressed patients are at increased risk for development of various cancers that comprise Kaposi's sarcoma (KS).To investigate the direct impact of immunosuppressive agents on Kaposi's sarcoma-associated herpesvirus (KSHV) and KS development, we quantified the effects of cyclosporine (CsA) and hydrocortisone (HC) on KSHV genome replication and the consequences on the cell survival.In the presence of phorbol ester 12-O-tetradecanoyl phorbol-13-acetate, we observed an increase of intracellular and extracellular KSHV DNA concomitantly with an increase of gp (glycoprotein) K8.1 expression, indicating KSHV genome replication. This replication was accompanied by cell apoptosis. In comparison, in the presence of CsA, HC, or both, we did not observe any effect on KSHV replication or gp K8.1 expression.Our results suggest that immunosuppressive agents such as HC and CsA do not activate the lytic cycle of KSHV and do not modify the cell survival thus promoting cancer progression by a direct cellular effect." @default.
- W1985958315 created "2016-06-24" @default.
- W1985958315 creator A5005911359 @default.
- W1985958315 creator A5026234029 @default.
- W1985958315 creator A5042447894 @default.
- W1985958315 creator A5048304227 @default.
- W1985958315 creator A5050061959 @default.
- W1985958315 creator A5060063338 @default.
- W1985958315 creator A5084209829 @default.
- W1985958315 date "2001-11-01" @default.
- W1985958315 modified "2023-10-18" @default.
- W1985958315 title "EFFECTS OF CYCLOSPORINE AND HYDROCORTISONE ON KAPOSI???S SARCOMA???ASSOCIATED HERPESVIRUS GENOME REPLICATION AND CELL APOPTOSIS INDUCTION1" @default.
- W1985958315 cites W1521598031 @default.
- W1985958315 cites W1787380229 @default.
- W1985958315 cites W2014571799 @default.
- W1985958315 cites W2051521205 @default.
- W1985958315 cites W2059258663 @default.
- W1985958315 cites W2115422513 @default.
- W1985958315 cites W2138051883 @default.
- W1985958315 cites W2157635632 @default.
- W1985958315 cites W2167882338 @default.
- W1985958315 cites W2168308593 @default.
- W1985958315 doi "https://doi.org/10.1097/00007890-200111270-00023" @default.
- W1985958315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11726836" @default.
- W1985958315 hasPublicationYear "2001" @default.
- W1985958315 type Work @default.
- W1985958315 sameAs 1985958315 @default.
- W1985958315 citedByCount "5" @default.
- W1985958315 countsByYear W19859583152012 @default.
- W1985958315 crossrefType "journal-article" @default.
- W1985958315 hasAuthorship W1985958315A5005911359 @default.
- W1985958315 hasAuthorship W1985958315A5026234029 @default.
- W1985958315 hasAuthorship W1985958315A5042447894 @default.
- W1985958315 hasAuthorship W1985958315A5048304227 @default.
- W1985958315 hasAuthorship W1985958315A5050061959 @default.
- W1985958315 hasAuthorship W1985958315A5060063338 @default.
- W1985958315 hasAuthorship W1985958315A5084209829 @default.
- W1985958315 hasBestOaLocation W19859583151 @default.
- W1985958315 hasConcept C109316439 @default.
- W1985958315 hasConcept C140704245 @default.
- W1985958315 hasConcept C1491633281 @default.
- W1985958315 hasConcept C159047783 @default.
- W1985958315 hasConcept C182615771 @default.
- W1985958315 hasConcept C190283241 @default.
- W1985958315 hasConcept C202751555 @default.
- W1985958315 hasConcept C203014093 @default.
- W1985958315 hasConcept C2522874641 @default.
- W1985958315 hasConcept C2776409557 @default.
- W1985958315 hasConcept C2780727368 @default.
- W1985958315 hasConcept C2780797929 @default.
- W1985958315 hasConcept C502942594 @default.
- W1985958315 hasConcept C54355233 @default.
- W1985958315 hasConcept C552990157 @default.
- W1985958315 hasConcept C62112901 @default.
- W1985958315 hasConcept C73573662 @default.
- W1985958315 hasConcept C73588182 @default.
- W1985958315 hasConcept C86803240 @default.
- W1985958315 hasConceptScore W1985958315C109316439 @default.
- W1985958315 hasConceptScore W1985958315C140704245 @default.
- W1985958315 hasConceptScore W1985958315C1491633281 @default.
- W1985958315 hasConceptScore W1985958315C159047783 @default.
- W1985958315 hasConceptScore W1985958315C182615771 @default.
- W1985958315 hasConceptScore W1985958315C190283241 @default.
- W1985958315 hasConceptScore W1985958315C202751555 @default.
- W1985958315 hasConceptScore W1985958315C203014093 @default.
- W1985958315 hasConceptScore W1985958315C2522874641 @default.
- W1985958315 hasConceptScore W1985958315C2776409557 @default.
- W1985958315 hasConceptScore W1985958315C2780727368 @default.
- W1985958315 hasConceptScore W1985958315C2780797929 @default.
- W1985958315 hasConceptScore W1985958315C502942594 @default.
- W1985958315 hasConceptScore W1985958315C54355233 @default.
- W1985958315 hasConceptScore W1985958315C552990157 @default.
- W1985958315 hasConceptScore W1985958315C62112901 @default.
- W1985958315 hasConceptScore W1985958315C73573662 @default.
- W1985958315 hasConceptScore W1985958315C73588182 @default.
- W1985958315 hasConceptScore W1985958315C86803240 @default.
- W1985958315 hasIssue "10" @default.
- W1985958315 hasLocation W19859583151 @default.
- W1985958315 hasLocation W19859583152 @default.
- W1985958315 hasLocation W19859583153 @default.
- W1985958315 hasOpenAccess W1985958315 @default.
- W1985958315 hasPrimaryLocation W19859583151 @default.
- W1985958315 hasRelatedWork W1536703076 @default.
- W1985958315 hasRelatedWork W1979414005 @default.
- W1985958315 hasRelatedWork W2040999715 @default.
- W1985958315 hasRelatedWork W2069532048 @default.
- W1985958315 hasRelatedWork W2100232224 @default.
- W1985958315 hasRelatedWork W2101259397 @default.
- W1985958315 hasRelatedWork W2157166895 @default.
- W1985958315 hasRelatedWork W3033987002 @default.
- W1985958315 hasRelatedWork W3152832187 @default.
- W1985958315 hasRelatedWork W2182712443 @default.
- W1985958315 hasVolume "72" @default.
- W1985958315 isParatext "false" @default.
- W1985958315 isRetracted "false" @default.
- W1985958315 magId "1985958315" @default.
- W1985958315 workType "article" @default.