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- W1985982246 abstract "Levels of blood glucose, lipid peroxidation, glutathione (GSH), glutathione peroxidase (GPx), glutathione S-transferase (GST) activities and blood selenium levels were determined in streptozotocin (STZ)-induced diabetic mice. The effect of oral administration of sodium selenite was studied on the above parameters. Diabetes caused hyperglycemia (2.8-fold increase) with a significant increase in the malondialdehyde levels (89% in liver and 83% in blood) and GST activity (55%) and marked decreases in GSH levels (approximately 73% in blood and 79% in liver) in the 5th week after STZ treatment as compared to normal control animals. Treatment of STZ-induced diabetic mice with sodium selenite changed these parameters to near control values in almost all cases. These results suggest that selenium plays a role in reducing the oxidative stress associated with diabetes." @default.
- W1985982246 created "2016-06-24" @default.
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- W1985982246 date "2004-04-01" @default.
- W1985982246 modified "2023-09-27" @default.
- W1985982246 title "M.675 Selenium blood concentration is incresed in patients with type 2 diabetes mellitus" @default.
- W1985982246 doi "https://doi.org/10.1016/s1567-5688(04)90673-9" @default.
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