Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985994490> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1985994490 endingPage "1381" @default.
- W1985994490 startingPage "1374" @default.
- W1985994490 abstract "Treatment of rabbits with sterile solutions of bovine Cu-Zn superoxide dismutase according to schedules recommended for radiation cystitis and radiation side effects has elicited the production of antibodies to the enzyme, detected in rabbit sera by a sensitive and specific radioimmunoassay. No antibodies were detected after a single treatment. However, on repeated administration of the enzyme all animals, including those that received 4 Gy whole body radiation prior to treatment, produced detectable antibody. Titers of antibody in sera rose progressively with repeated injections of the enzyme. Irradiation served merely to delay the onset of the immune response. In addition, human and bovine Cu-Zn superoxide dismutase have been found to be antigenically distinct when examined by competitive inhibition radioimmunoassay. These antigenic differences and the immunogenicity of the bovine enzyme in rabbits raise reasonable doubt as to the safety of administration of bovine superoxide dismutase to human patients. It is recommended that such patients be monitored for antibody production, preferably by radioimmunoassay." @default.
- W1985994490 created "2016-06-24" @default.
- W1985994490 creator A5017789889 @default.
- W1985994490 creator A5038309767 @default.
- W1985994490 creator A5050162128 @default.
- W1985994490 creator A5089717543 @default.
- W1985994490 date "1982-11-01" @default.
- W1985994490 modified "2023-09-26" @default.
- W1985994490 title "On the safety of treatment with bovine superoxide dismutase: production of a humoral antibody response in rabbits with repeated treatment" @default.
- W1985994490 cites W1509659678 @default.
- W1985994490 cites W1627176510 @default.
- W1985994490 cites W2052833901 @default.
- W1985994490 cites W2085244473 @default.
- W1985994490 cites W2135158074 @default.
- W1985994490 cites W2144815963 @default.
- W1985994490 doi "https://doi.org/10.1139/y82-205" @default.
- W1985994490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7151007" @default.
- W1985994490 hasPublicationYear "1982" @default.
- W1985994490 type Work @default.
- W1985994490 sameAs 1985994490 @default.
- W1985994490 citedByCount "11" @default.
- W1985994490 crossrefType "journal-article" @default.
- W1985994490 hasAuthorship W1985994490A5017789889 @default.
- W1985994490 hasAuthorship W1985994490A5038309767 @default.
- W1985994490 hasAuthorship W1985994490A5050162128 @default.
- W1985994490 hasAuthorship W1985994490A5089717543 @default.
- W1985994490 hasConcept C147483822 @default.
- W1985994490 hasConcept C153911025 @default.
- W1985994490 hasConcept C159654299 @default.
- W1985994490 hasConcept C176685330 @default.
- W1985994490 hasConcept C181199279 @default.
- W1985994490 hasConcept C185592680 @default.
- W1985994490 hasConcept C203014093 @default.
- W1985994490 hasConcept C22889606 @default.
- W1985994490 hasConcept C2775838275 @default.
- W1985994490 hasConcept C2780868878 @default.
- W1985994490 hasConcept C32611913 @default.
- W1985994490 hasConcept C55493867 @default.
- W1985994490 hasConcept C86803240 @default.
- W1985994490 hasConcept C8891405 @default.
- W1985994490 hasConceptScore W1985994490C147483822 @default.
- W1985994490 hasConceptScore W1985994490C153911025 @default.
- W1985994490 hasConceptScore W1985994490C159654299 @default.
- W1985994490 hasConceptScore W1985994490C176685330 @default.
- W1985994490 hasConceptScore W1985994490C181199279 @default.
- W1985994490 hasConceptScore W1985994490C185592680 @default.
- W1985994490 hasConceptScore W1985994490C203014093 @default.
- W1985994490 hasConceptScore W1985994490C22889606 @default.
- W1985994490 hasConceptScore W1985994490C2775838275 @default.
- W1985994490 hasConceptScore W1985994490C2780868878 @default.
- W1985994490 hasConceptScore W1985994490C32611913 @default.
- W1985994490 hasConceptScore W1985994490C55493867 @default.
- W1985994490 hasConceptScore W1985994490C86803240 @default.
- W1985994490 hasConceptScore W1985994490C8891405 @default.
- W1985994490 hasIssue "11" @default.
- W1985994490 hasLocation W19859944901 @default.
- W1985994490 hasLocation W19859944902 @default.
- W1985994490 hasOpenAccess W1985994490 @default.
- W1985994490 hasPrimaryLocation W19859944901 @default.
- W1985994490 hasRelatedWork W1922452316 @default.
- W1985994490 hasRelatedWork W1934038313 @default.
- W1985994490 hasRelatedWork W1985994490 @default.
- W1985994490 hasRelatedWork W2018354288 @default.
- W1985994490 hasRelatedWork W2043807987 @default.
- W1985994490 hasRelatedWork W2048230388 @default.
- W1985994490 hasRelatedWork W2137534003 @default.
- W1985994490 hasRelatedWork W2313397507 @default.
- W1985994490 hasRelatedWork W2359884338 @default.
- W1985994490 hasRelatedWork W2411114470 @default.
- W1985994490 hasVolume "60" @default.
- W1985994490 isParatext "false" @default.
- W1985994490 isRetracted "false" @default.
- W1985994490 magId "1985994490" @default.
- W1985994490 workType "article" @default.