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- W1986083721 abstract "Potassium and sodium thiocyanate have been used in the treatment of hypertension since their introduction to clinical medicine in 1903. At least 14,000 lb. was prescribed for medicinal purposes in the U. S. in 1952. Although their mode of action is not yet fully understood, proper administration of these drugs will produce a significant drop in blood pressure in about 50% of patients. In addition, thiocyanates often succeed in controlling hypertensive headaches that are resistant to other forms of treatment. The deleterious effects of the improper use of thiocyanates have been frequently stressed. In 1932, Gold-ring and Chasis reported the first fatalities from the therapeutic use of this drug. Fifty hypertensive patients were given a total of 74 series of treatments with either potassium or sodium thiocyanate under carefully studied conditions. Untoward reactions occurred 13 times in the series (an incidence of 17%), and 2 of the 50 patients died" @default.
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- W1986083721 date "1955-06-18" @default.
- W1986083721 modified "2023-09-25" @default.
- W1986083721 title "USE OF THE ARTIFICIAL KIDNEY IN TREATMENT OF THIOCYANATE PSYCHOSIS" @default.
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- W1986083721 doi "https://doi.org/10.1001/jama.1955.02960070036010" @default.
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