Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986118244> ?p ?o ?g. }
- W1986118244 endingPage "249" @default.
- W1986118244 startingPage "239" @default.
- W1986118244 abstract "Peroxiredoxins (Prxs) play an important role against various oxidative stresses and intra-cellular signal transduction. Peroxiredoxin 6 (PrxVI) was identified from the disk abalone Haliotis discus discus cDNA library and named HdPrxVI. The full length cDNA of HdPrxVI was 1457 bp with a 654 bp open reading frame (ORF) encoding 218 amino acids. The predicted molecular mass and estimated isoelectric point (pI) of HdPrxVI were 24 kDa and 7.3, respectively. The deduced amino acid sequence demonstrated the greatest degree (72.4%) of identity with Crassostrea gigas PrxVI. The conserved peroxidase catalytic center (42PVCTTE47) with a conserved cysteine residue (Cys44) and a catalytic center for PLA2 activity (27GGSWA31) were observed in the sequence, indicating that it is a member of 1-Cys Prx. Real time PCR results revealed that HdPrxVI mRNA is constitutively expressed in all tissues in a tissue-specific manner. During exposure to haemorrhagic septicaemia virus (VHSV), HdPrxVI mRNA transcription was down-regulated in the gill, suggesting that the abalone responded to the viral infection quickly, and HdPrxVI played a physiological role against virus-induced oxidative stress. The purified recombinant HdPrxVI, together with dithiothreitol (DTT), was shown to scavenge H2O2 in human leukemia THP-1 cells and provided protection against H2O2-induced apoptosis." @default.
- W1986118244 created "2016-06-24" @default.
- W1986118244 creator A5004072373 @default.
- W1986118244 creator A5004319038 @default.
- W1986118244 creator A5005733902 @default.
- W1986118244 creator A5030480121 @default.
- W1986118244 creator A5058672519 @default.
- W1986118244 creator A5077269914 @default.
- W1986118244 creator A5085283871 @default.
- W1986118244 date "2009-08-01" @default.
- W1986118244 modified "2023-09-25" @default.
- W1986118244 title "Molecular cloning, characterization and expression analysis of peroxiredoxin 6 from disk abalone Haliotis discus discus and the antioxidant activity of its recombinant protein" @default.
- W1986118244 cites W1525149396 @default.
- W1986118244 cites W1589043152 @default.
- W1986118244 cites W1595716614 @default.
- W1986118244 cites W1964357843 @default.
- W1986118244 cites W1964617786 @default.
- W1986118244 cites W1966728645 @default.
- W1986118244 cites W1967099953 @default.
- W1986118244 cites W1968779255 @default.
- W1986118244 cites W1974872163 @default.
- W1986118244 cites W1975695039 @default.
- W1986118244 cites W1979803581 @default.
- W1986118244 cites W1980866054 @default.
- W1986118244 cites W1985776151 @default.
- W1986118244 cites W1986883956 @default.
- W1986118244 cites W1989374719 @default.
- W1986118244 cites W1995002748 @default.
- W1986118244 cites W1995579093 @default.
- W1986118244 cites W1999392732 @default.
- W1986118244 cites W2002905535 @default.
- W1986118244 cites W2016241657 @default.
- W1986118244 cites W2017319917 @default.
- W1986118244 cites W2027181772 @default.
- W1986118244 cites W2034047922 @default.
- W1986118244 cites W2041115865 @default.
- W1986118244 cites W2042698393 @default.
- W1986118244 cites W2048310559 @default.
- W1986118244 cites W2049110705 @default.
- W1986118244 cites W2057016112 @default.
- W1986118244 cites W2059392338 @default.
- W1986118244 cites W2064789974 @default.
- W1986118244 cites W2066976946 @default.
- W1986118244 cites W2069137433 @default.
- W1986118244 cites W2074380027 @default.
- W1986118244 cites W2075480853 @default.
- W1986118244 cites W2078849009 @default.
- W1986118244 cites W2079292646 @default.
- W1986118244 cites W2083354074 @default.
- W1986118244 cites W2084156415 @default.
- W1986118244 cites W2087160136 @default.
- W1986118244 cites W2092463196 @default.
- W1986118244 cites W2093783786 @default.
- W1986118244 cites W2094747611 @default.
- W1986118244 cites W2095260224 @default.
- W1986118244 cites W2107277218 @default.
- W1986118244 cites W2115201656 @default.
- W1986118244 cites W2116212096 @default.
- W1986118244 cites W2146396346 @default.
- W1986118244 cites W2158496331 @default.
- W1986118244 cites W2168082981 @default.
- W1986118244 cites W4293247451 @default.
- W1986118244 doi "https://doi.org/10.1016/j.fsi.2009.05.002" @default.
- W1986118244 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19460442" @default.
- W1986118244 hasPublicationYear "2009" @default.
- W1986118244 type Work @default.
- W1986118244 sameAs 1986118244 @default.
- W1986118244 citedByCount "37" @default.
- W1986118244 countsByYear W19861182442012 @default.
- W1986118244 countsByYear W19861182442013 @default.
- W1986118244 countsByYear W19861182442014 @default.
- W1986118244 countsByYear W19861182442015 @default.
- W1986118244 countsByYear W19861182442016 @default.
- W1986118244 countsByYear W19861182442017 @default.
- W1986118244 countsByYear W19861182442018 @default.
- W1986118244 countsByYear W19861182442019 @default.
- W1986118244 countsByYear W19861182442020 @default.
- W1986118244 countsByYear W19861182442021 @default.
- W1986118244 countsByYear W19861182442022 @default.
- W1986118244 crossrefType "journal-article" @default.
- W1986118244 hasAuthorship W1986118244A5004072373 @default.
- W1986118244 hasAuthorship W1986118244A5004319038 @default.
- W1986118244 hasAuthorship W1986118244A5005733902 @default.
- W1986118244 hasAuthorship W1986118244A5030480121 @default.
- W1986118244 hasAuthorship W1986118244A5058672519 @default.
- W1986118244 hasAuthorship W1986118244A5077269914 @default.
- W1986118244 hasAuthorship W1986118244A5085283871 @default.
- W1986118244 hasConcept C104317684 @default.
- W1986118244 hasConcept C153911025 @default.
- W1986118244 hasConcept C162008176 @default.
- W1986118244 hasConcept C167625842 @default.
- W1986118244 hasConcept C181199279 @default.
- W1986118244 hasConcept C187882448 @default.
- W1986118244 hasConcept C19924922 @default.
- W1986118244 hasConcept C2775933076 @default.
- W1986118244 hasConcept C2780416994 @default.
- W1986118244 hasConcept C2780982499 @default.
- W1986118244 hasConcept C40767141 @default.