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- W1986178825 abstract "We designed a post-induction therapy including intensive sequential therapy with non-cross-resistant drugs in an effort to prolong disease-free survival (DFS) for adults with acute myelogenous leukemia. Forty-five patients entered this study and 33 of 35 patients entering complete remission received the post-induction therapy. With a median follow-up for survivors of 3.5 years from complete remission, the actuarial 5-year DFS was 46% +/- 19% (95% confidence interval). The five-year DFS for patients over 45 years of age was comparable to that for patients under 45 years of age (50% +/- 26% vs 47% +/- 28%). Furthermore, the actuarial 5-year DFS for patients who required two courses of induction therapy was comparable to that for patients who required only one course of induction therapy (45% +/- 29% vs 50% +/- 25%). The toxicity of post-induction therapy was tolerable and no patients died during complete remission." @default.
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- W1986178825 date "1992-06-01" @default.
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- W1986178825 title "Intensive sequential post-induction therapy for adults with acute myelogenous leukemia in first remission: Long-term follow-up and results" @default.
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- W1986178825 doi "https://doi.org/10.1016/0145-2126(92)90005-r" @default.
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