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- W1986239407 abstract "The granulocyte is normally thought of as a friendly cell, important to the host’s ability to defend against microbial invaders. Certainly, this is an important role, as evidenced by the infection propensity seen in patients with functional abnormalities of granulocytes or with extreme granulocytopenia. As early as 1887, Metchnikoff suggested that stimulated granulocytes might be also capable of doing harm. He postulated that “ferments” released from the cells at the site of inflammation might be capable of damaging host tissues, and might therefore be a part of the inflammatory reaction. In the last few decades, this idea has been refined as granulocyte function has become better understood; it survives as the “frustrated phagocytosis” model of immune tissue injury described by Henson 2 Hensen PM The immunological release of constituents from neutrophil leukocytes. J Immunol. 1971; 107: 1525-1557 Google Scholar (Fig 1) ." @default.
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- W1986239407 date "1983-05-01" @default.
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- W1986239407 title "Leukocytes in Lung Injury" @default.
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