FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986249401> ?p ?o ?g. }

• W1986249401 endingPage "428" @default.
• W1986249401 startingPage "425" @default.
• W1986249401 abstract "This study was designed to retrospectively evaluate the efficacy and safety of modified FOLFOX-6 regimen in advanced gastric cancer (AGC) patients with poor performance status (PS). From January 2005 to August 2010, 23 AGC patients with poor PS who received mFOLFOX-6 as first-line chemotherapy were reviewed. Patients received 100 mg/m(2) oxaliplatin and 100 mg/m(2) leucovorin (LV) as a 2-h intravenous infusion on day 1, followed by 5-fluorouracil (5-FU) at 2000 mg/m(2) as a 46-h continuous infusion. A total of 22 patients received more than 3 cycles of chemotherapy and were evaluable for tumor response. Seven patients achieved partial response, giving an overall response rate of 31.8%. The median time to progression and overall survival were 3.5 and 9.2 months, respectively. Grade 3-4 hematological toxicities were noted: neutropenia in four patients (17.4%), anemia in two (8.7%) and thrombocytopenia in one (4.3%). Two patients developed febrile neutropenia and one of these patients succumbed to sepsis. Grade 3-4 gastrointestinal toxicities, such as nausea, vomiting and diarrhea were observed in less than 10% of patients. Peripheral neuropathy was observed in 9 patients (39.1%). In conclusion, the mFOLFOX-6 regimen for AGC patients with poor PS was effective with acceptable toxicity. Our results suggest that this regimen may be an effective option for these patients." @default.
• W1986249401 created "2016-06-24" @default.
• W1986249401 creator A5026612909 @default.
• W1986249401 creator A5029499836 @default.
• W1986249401 creator A5033156197 @default.
• W1986249401 creator A5044201544 @default.
• W1986249401 creator A5044483735 @default.
• W1986249401 creator A5044939437 @default.
• W1986249401 creator A5055814473 @default.
• W1986249401 creator A5063892435 @default.
• W1986249401 creator A5066094957 @default.
• W1986249401 creator A5070418550 @default.
• W1986249401 creator A5070925239 @default.
• W1986249401 creator A5083905576 @default.
• W1986249401 creator A5084870834 @default.
• W1986249401 date "2011-11-25" @default.
• W1986249401 modified "2023-09-30" @default.
• W1986249401 title "Oxaliplatin, 5-fluorouracil and leucovorin (modified FOLFOX-6) as first-line chemotherapy for advanced gastric cancer patients with poor performance status" @default.
• W1986249401 cites W1990945921 @default.
• W1986249401 cites W1993733741 @default.
• W1986249401 cites W2034162342 @default.
• W1986249401 cites W2060704373 @default.
• W1986249401 cites W2078040823 @default.
• W1986249401 cites W2104958199 @default.
• W1986249401 cites W2118247947 @default.
• W1986249401 cites W2121368761 @default.
• W1986249401 cites W2123495698 @default.
• W1986249401 cites W2123927174 @default.
• W1986249401 cites W2127187776 @default.
• W1986249401 cites W2128775037 @default.
• W1986249401 cites W2917026948 @default.
• W1986249401 cites W4252125722 @default.
• W1986249401 doi "https://doi.org/10.3892/ol.2011.496" @default.
• W1986249401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3362383" @default.
• W1986249401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22740925" @default.
• W1986249401 hasPublicationYear "2011" @default.
• W1986249401 type Work @default.
• W1986249401 sameAs 1986249401 @default.
• W1986249401 citedByCount "11" @default.
• W1986249401 countsByYear W19862494012014 @default.
• W1986249401 countsByYear W19862494012015 @default.
• W1986249401 countsByYear W19862494012016 @default.
• W1986249401 countsByYear W19862494012018 @default.
• W1986249401 countsByYear W19862494012019 @default.
• W1986249401 countsByYear W19862494012020 @default.
• W1986249401 crossrefType "journal-article" @default.
• W1986249401 hasAuthorship W1986249401A5026612909 @default.
• W1986249401 hasAuthorship W1986249401A5029499836 @default.
• W1986249401 hasAuthorship W1986249401A5033156197 @default.
• W1986249401 hasAuthorship W1986249401A5044201544 @default.
• W1986249401 hasAuthorship W1986249401A5044483735 @default.
• W1986249401 hasAuthorship W1986249401A5044939437 @default.
• W1986249401 hasAuthorship W1986249401A5055814473 @default.
• W1986249401 hasAuthorship W1986249401A5063892435 @default.
• W1986249401 hasAuthorship W1986249401A5066094957 @default.
• W1986249401 hasAuthorship W1986249401A5070418550 @default.
• W1986249401 hasAuthorship W1986249401A5070925239 @default.
• W1986249401 hasAuthorship W1986249401A5083905576 @default.
• W1986249401 hasAuthorship W1986249401A5084870834 @default.
• W1986249401 hasBestOaLocation W19862494011 @default.
• W1986249401 hasConcept C121608353 @default.
• W1986249401 hasConcept C126322002 @default.
• W1986249401 hasConcept C141071460 @default.
• W1986249401 hasConcept C2776694085 @default.
• W1986249401 hasConcept C2776907518 @default.
• W1986249401 hasConcept C2777063308 @default.
• W1986249401 hasConcept C2778248108 @default.
• W1986249401 hasConcept C2778260052 @default.
• W1986249401 hasConcept C2780456651 @default.
• W1986249401 hasConcept C2780580376 @default.
• W1986249401 hasConcept C2780852908 @default.
• W1986249401 hasConcept C2780962732 @default.
• W1986249401 hasConcept C2781413609 @default.
• W1986249401 hasConcept C526805850 @default.
• W1986249401 hasConcept C71924100 @default.
• W1986249401 hasConcept C90924648 @default.
• W1986249401 hasConceptScore W1986249401C121608353 @default.
• W1986249401 hasConceptScore W1986249401C126322002 @default.
• W1986249401 hasConceptScore W1986249401C141071460 @default.
• W1986249401 hasConceptScore W1986249401C2776694085 @default.
• W1986249401 hasConceptScore W1986249401C2776907518 @default.
• W1986249401 hasConceptScore W1986249401C2777063308 @default.
• W1986249401 hasConceptScore W1986249401C2778248108 @default.
• W1986249401 hasConceptScore W1986249401C2778260052 @default.
• W1986249401 hasConceptScore W1986249401C2780456651 @default.
• W1986249401 hasConceptScore W1986249401C2780580376 @default.
• W1986249401 hasConceptScore W1986249401C2780852908 @default.
• W1986249401 hasConceptScore W1986249401C2780962732 @default.
• W1986249401 hasConceptScore W1986249401C2781413609 @default.
• W1986249401 hasConceptScore W1986249401C526805850 @default.
• W1986249401 hasConceptScore W1986249401C71924100 @default.
• W1986249401 hasConceptScore W1986249401C90924648 @default.
• W1986249401 hasIssue "2" @default.
• W1986249401 hasLocation W19862494011 @default.
• W1986249401 hasLocation W19862494012 @default.
• W1986249401 hasLocation W19862494013 @default.
• W1986249401 hasLocation W19862494014 @default.
• W1986249401 hasOpenAccess W1986249401 @default.

• next