FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986255967> ?p ?o ?g. }

• W1986255967 endingPage "228" @default.
• W1986255967 startingPage "215" @default.
• W1986255967 abstract "Subtilase cytotoxin (SubAB) is the prototype of a new AB5 toxin family produced by a subset of Shiga toxigenic Escherichia coli (STEC) strains. Its A subunit is a subtilase-like serine protease and cytotoxicity for eukaryotic cells is due to a highly specific, single-site cleavage of BiP/GRP78, an essential Hsp70 family chaperone located in the endoplasmic reticulum (ER). This cleavage triggers a severe and unresolved ER stress response, ultimately triggering apoptosis. The B subunit has specificity for glycans terminating in the sialic acid N-glycolylneuraminic acid. Although its actual role in human disease pathogenesis is yet to be established, SubAB is lethal for mice and induces pathological features overlapping those seen in the haemolytic uraemic syndrome, a life-threatening complication of STEC infection. The toxin is also proving to be a useful tool for probing the role of BiP and ER stress in a variety of cellular functions." @default.
• W1986255967 created "2016-06-24" @default.
• W1986255967 creator A5038494526 @default.
• W1986255967 creator A5055597053 @default.
• W1986255967 date "2010-01-28" @default.
• W1986255967 modified "2023-10-16" @default.
• W1986255967 title "Escherichia coli Subtilase Cytotoxin" @default.
• W1986255967 cites W1567375657 @default.
• W1986255967 cites W1573490928 @default.
• W1986255967 cites W1585642123 @default.
• W1986255967 cites W1592978302 @default.
• W1986255967 cites W1901625012 @default.
• W1986255967 cites W1915521551 @default.
• W1986255967 cites W1963982744 @default.
• W1986255967 cites W1967006303 @default.
• W1986255967 cites W1985317246 @default.
• W1986255967 cites W2000006041 @default.
• W1986255967 cites W2008328982 @default.
• W1986255967 cites W2014537095 @default.
• W1986255967 cites W2027231620 @default.
• W1986255967 cites W2027727753 @default.
• W1986255967 cites W2028603831 @default.
• W1986255967 cites W2036915650 @default.
• W1986255967 cites W2038527888 @default.
• W1986255967 cites W2043476221 @default.
• W1986255967 cites W2045900690 @default.
• W1986255967 cites W2048846412 @default.
• W1986255967 cites W2050013500 @default.
• W1986255967 cites W2051606402 @default.
• W1986255967 cites W2054072307 @default.
• W1986255967 cites W2055338783 @default.
• W1986255967 cites W2065827134 @default.
• W1986255967 cites W2072610101 @default.
• W1986255967 cites W2072617498 @default.
• W1986255967 cites W2073304789 @default.
• W1986255967 cites W2074755659 @default.
• W1986255967 cites W2079473693 @default.
• W1986255967 cites W2080736015 @default.
• W1986255967 cites W2092200886 @default.
• W1986255967 cites W2093942030 @default.
• W1986255967 cites W2094264753 @default.
• W1986255967 cites W2094775539 @default.
• W1986255967 cites W2100630873 @default.
• W1986255967 cites W2103798600 @default.
• W1986255967 cites W2110101671 @default.
• W1986255967 cites W2115177266 @default.
• W1986255967 cites W2115626643 @default.
• W1986255967 cites W2116792521 @default.
• W1986255967 cites W2117445500 @default.
• W1986255967 cites W2117614106 @default.
• W1986255967 cites W2118685458 @default.
• W1986255967 cites W2119866976 @default.
• W1986255967 cites W2123994723 @default.
• W1986255967 cites W2128547513 @default.
• W1986255967 cites W2128975348 @default.
• W1986255967 cites W2129058679 @default.
• W1986255967 cites W2132276253 @default.
• W1986255967 cites W2133644385 @default.
• W1986255967 cites W2136482421 @default.
• W1986255967 cites W2141326811 @default.
• W1986255967 cites W2145813968 @default.
• W1986255967 cites W2157848930 @default.
• W1986255967 cites W2159364591 @default.
• W1986255967 cites W2171183281 @default.
• W1986255967 cites W4243603314 @default.
• W1986255967 doi "https://doi.org/10.3390/toxins2020215" @default.
• W1986255967 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2943149" @default.
• W1986255967 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20871837" @default.
• W1986255967 hasPublicationYear "2010" @default.
• W1986255967 type Work @default.
• W1986255967 sameAs 1986255967 @default.
• W1986255967 citedByCount "47" @default.
• W1986255967 countsByYear W19862559672012 @default.
• W1986255967 countsByYear W19862559672013 @default.
• W1986255967 countsByYear W19862559672014 @default.
• W1986255967 countsByYear W19862559672015 @default.
• W1986255967 countsByYear W19862559672016 @default.
• W1986255967 countsByYear W19862559672017 @default.
• W1986255967 countsByYear W19862559672018 @default.
• W1986255967 countsByYear W19862559672019 @default.
• W1986255967 countsByYear W19862559672020 @default.
• W1986255967 countsByYear W19862559672021 @default.
• W1986255967 countsByYear W19862559672022 @default.
• W1986255967 countsByYear W19862559672023 @default.
• W1986255967 crossrefType "journal-article" @default.
• W1986255967 hasAuthorship W1986255967A5038494526 @default.
• W1986255967 hasAuthorship W1986255967A5055597053 @default.
• W1986255967 hasBestOaLocation W19862559671 @default.
• W1986255967 hasConcept C104292427 @default.
• W1986255967 hasConcept C104317684 @default.
• W1986255967 hasConcept C119062480 @default.
• W1986255967 hasConcept C139447449 @default.
• W1986255967 hasConcept C142724271 @default.
• W1986255967 hasConcept C158617107 @default.
• W1986255967 hasConcept C181199279 @default.
• W1986255967 hasConcept C203014093 @default.
• W1986255967 hasConcept C2775962898 @default.
• W1986255967 hasConcept C2776714187 @default.

• next