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- W1986288661 abstract "The effectiveness of three concentrations of sodium hypochlorite in the detoxification of two different endotoxins, Escherichia coli w(0127:B8) and Salmonella typhosa w(0901) was studied. The in vitro Pyrostat limulus amoebocyte lysate assay system was adapted to quantitatively determine the detoxifying effect of 0.58%, 2.70%, and 5.20% NaOCl on endotoxin when the solution and endotoxin were combined for one hour at room temperature. The results indicated that all three concentrations were equally effective in completely detoxifying the largest amount of either endotoxin studied (100 ng/ml solution). An in vivo pilot procedure was developed to test the effect of NaOCl on larger amounts of endotoxin. The results indicated that 1 ml of 0.58% or 2.7% does not detoxify large amounts of E coli endotoxin (2,000 μg/1 ml solution). The results using 5.20% NaOCl were inconclusive." @default.
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- W1986288661 date "1982-02-01" @default.
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- W1986288661 title "The detoxifying effect of varying concentrations of sodium hypochlorite on endotoxins" @default.
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- W1986288661 doi "https://doi.org/10.1016/s0099-2399(82)80259-8" @default.
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