Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986320552> ?p ?o ?g. }
- W1986320552 endingPage "72" @default.
- W1986320552 startingPage "63" @default.
- W1986320552 abstract "The Hedgehog (Hh) pathway has become an important model to study the cell biology of primary cilia, and reciprocally, the study of ciliary processes provides an opportunity to solve longstanding mysteries in the mechanism of vertebrate Hh signal transduction. The cilium is emerging as an unique compartment for G-protein-coupled receptor (GPCR) signaling in many systems. Two members of the GPCR family, Smoothened and Gpr161, play important roles in the Hh pathway. We review the current understanding of how these proteins may function to regulate Hh signaling and also highlight some of the critical unanswered questions being tackled by the field. Uncovering GPCR-regulated mechanisms important in Hh signaling may provide therapeutic strategies against the Hh pathway that plays important roles in development, regeneration and cancer." @default.
- W1986320552 created "2016-06-24" @default.
- W1986320552 creator A5024389946 @default.
- W1986320552 creator A5055546235 @default.
- W1986320552 date "2014-09-01" @default.
- W1986320552 modified "2023-10-16" @default.
- W1986320552 title "G-protein-coupled receptors, Hedgehog signaling and primary cilia" @default.
- W1986320552 cites W1481472040 @default.
- W1986320552 cites W1543890504 @default.
- W1986320552 cites W1580962701 @default.
- W1986320552 cites W1722148928 @default.
- W1986320552 cites W1959046600 @default.
- W1986320552 cites W1963493384 @default.
- W1986320552 cites W1963807253 @default.
- W1986320552 cites W1966998932 @default.
- W1986320552 cites W1971060771 @default.
- W1986320552 cites W1974043427 @default.
- W1986320552 cites W1974094726 @default.
- W1986320552 cites W1976421227 @default.
- W1986320552 cites W1979067492 @default.
- W1986320552 cites W1981691061 @default.
- W1986320552 cites W1983341583 @default.
- W1986320552 cites W1985661051 @default.
- W1986320552 cites W1986184460 @default.
- W1986320552 cites W1987913532 @default.
- W1986320552 cites W1988097700 @default.
- W1986320552 cites W1991138299 @default.
- W1986320552 cites W1993416164 @default.
- W1986320552 cites W1993465232 @default.
- W1986320552 cites W1995078993 @default.
- W1986320552 cites W1995651171 @default.
- W1986320552 cites W1997628120 @default.
- W1986320552 cites W1999100324 @default.
- W1986320552 cites W2001161463 @default.
- W1986320552 cites W2001173847 @default.
- W1986320552 cites W2002249795 @default.
- W1986320552 cites W2007764395 @default.
- W1986320552 cites W2011070056 @default.
- W1986320552 cites W2012535690 @default.
- W1986320552 cites W2012863615 @default.
- W1986320552 cites W2015382764 @default.
- W1986320552 cites W2015557754 @default.
- W1986320552 cites W2016654953 @default.
- W1986320552 cites W2017400416 @default.
- W1986320552 cites W2021193175 @default.
- W1986320552 cites W2022877314 @default.
- W1986320552 cites W2023724239 @default.
- W1986320552 cites W2026755963 @default.
- W1986320552 cites W2027415486 @default.
- W1986320552 cites W2029500889 @default.
- W1986320552 cites W2032792789 @default.
- W1986320552 cites W2036833206 @default.
- W1986320552 cites W2040182956 @default.
- W1986320552 cites W2040203747 @default.
- W1986320552 cites W2040279612 @default.
- W1986320552 cites W2043289157 @default.
- W1986320552 cites W2044753677 @default.
- W1986320552 cites W2048262130 @default.
- W1986320552 cites W2049484225 @default.
- W1986320552 cites W2049859215 @default.
- W1986320552 cites W2051301625 @default.
- W1986320552 cites W2053351302 @default.
- W1986320552 cites W2053385369 @default.
- W1986320552 cites W2059614045 @default.
- W1986320552 cites W2061616166 @default.
- W1986320552 cites W2061684132 @default.
- W1986320552 cites W2063299495 @default.
- W1986320552 cites W2063340261 @default.
- W1986320552 cites W2066480724 @default.
- W1986320552 cites W2066711817 @default.
- W1986320552 cites W2068661995 @default.
- W1986320552 cites W2070184849 @default.
- W1986320552 cites W2070524647 @default.
- W1986320552 cites W2071435286 @default.
- W1986320552 cites W2071781502 @default.
- W1986320552 cites W2072547641 @default.
- W1986320552 cites W2072618030 @default.
- W1986320552 cites W2072917759 @default.
- W1986320552 cites W2073521369 @default.
- W1986320552 cites W2074314807 @default.
- W1986320552 cites W2075126779 @default.
- W1986320552 cites W2075994912 @default.
- W1986320552 cites W2078725182 @default.
- W1986320552 cites W2083249373 @default.
- W1986320552 cites W2083701433 @default.
- W1986320552 cites W2083988049 @default.
- W1986320552 cites W2085132889 @default.
- W1986320552 cites W2085356690 @default.
- W1986320552 cites W2085775776 @default.
- W1986320552 cites W2090455515 @default.
- W1986320552 cites W2091684557 @default.
- W1986320552 cites W2094092533 @default.
- W1986320552 cites W2094399319 @default.
- W1986320552 cites W2095243783 @default.
- W1986320552 cites W2095486148 @default.
- W1986320552 cites W2097514247 @default.
- W1986320552 cites W2099118069 @default.
- W1986320552 cites W2099970745 @default.