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- W1986390146 abstract "Previous work from this department has showa that estrogen, like dietary cholesterol, raises blood cholesterol levels in the chicken. Unlike cholesterol feeding, however, estrogens produce an even greater rise in blood phospholipids so that the cholesterolj phospholipid (CjP) ratio in the blood declines whereas in cholesterol feeding the CfP ratio rises l . Estrogens also have the remarkable effect of preventing coronary atherosclerosis in chickens usually induced by a high cholesterol-oil diet, and causing such induced lesions to disappear2 ,3. This effect is peculiar to the coronary vessels. In the aorta, estrogens do not appear to prevent or reverse the atherosclerotic process induced by a high cholesterol diet2, and actually can produce such lesions per se by raising blood cholesterol. However, high doses of estrogens produce ulceration of atheromatous plaques in the abdominal aorta and in the coronary vessels4• These estrogen effects may depend on the change in the distribution of the blood lipids as shown by the reversal of the C/P ratio and the a/ fJ lipoprotein rati057. Estrogen action also involves an effect via the reticulo-endothelial system in the chickens. This report deals with some preliminary observations which suggest that estrogens modify the concentration of bile cholesterol. The observations on bile cholesterol concentration were made during the course of developing a bile fistula technique in chickens." @default.
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- W1986390146 date "1963-01-01" @default.
- W1986390146 modified "2023-09-26" @default.
- W1986390146 title "The effect of estrogen on the concentration of bile cholesterol in the chicken" @default.
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- W1986390146 doi "https://doi.org/10.1016/s0368-1319(63)80099-x" @default.
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