Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986444218> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1986444218 endingPage "265" @default.
- W1986444218 startingPage "262" @default.
- W1986444218 abstract "The role of oxygen free radical generation during reversible focal cerebral ischemia and its relationship to nitric oxide mediated mechanisms were examined. In this study, a left frontal cortex microdialysis probe was placed into the previously defined ischemic penumbra region and perfused with a salicylate/CSF solution in the presence or absence of the nitric oxide synthase (NOS) inhibitor L-NAME. Rats were then subjected to transient left hemisphere focal cerebral ischemia. Dialysate was collected at baseline and during the ischemic/reperfusion phase, and the hydroxylation products of salicylate were measured by HPLC with electrochemical detection. A significant elevation of free radical adduct formation was observed in the penumbra region during ischemia/reperfusion. This elevation was significantly attenuated by L-NAME during the reperfusion phase. Elevation of free radical adduct formation within the penumbra region during cerebral ischemia/reperfusion may be mediated in part by NOS-dependent mechanisms." @default.
- W1986444218 created "2016-06-24" @default.
- W1986444218 creator A5010067320 @default.
- W1986444218 creator A5027030592 @default.
- W1986444218 date "2000-04-01" @default.
- W1986444218 modified "2023-10-16" @default.
- W1986444218 title "Attenuation of free radical generation during reversible focal cerebral ischemia with the nitric oxide inhibitor, l-NAME (l-NG-nitro-l-arginine methyl ester)" @default.
- W1986444218 cites W1667686291 @default.
- W1986444218 cites W1975941571 @default.
- W1986444218 cites W1976541392 @default.
- W1986444218 cites W1979051785 @default.
- W1986444218 cites W1985221375 @default.
- W1986444218 cites W1988333213 @default.
- W1986444218 cites W1999220416 @default.
- W1986444218 cites W2003300261 @default.
- W1986444218 cites W2011233979 @default.
- W1986444218 cites W2028676745 @default.
- W1986444218 cites W2044688976 @default.
- W1986444218 cites W2047843548 @default.
- W1986444218 cites W2055524735 @default.
- W1986444218 cites W2067494203 @default.
- W1986444218 cites W2068869692 @default.
- W1986444218 cites W2074187719 @default.
- W1986444218 cites W2082707311 @default.
- W1986444218 cites W2085366528 @default.
- W1986444218 cites W2085935168 @default.
- W1986444218 cites W2089981038 @default.
- W1986444218 cites W2100358219 @default.
- W1986444218 cites W2140936548 @default.
- W1986444218 cites W2152091665 @default.
- W1986444218 cites W2162716309 @default.
- W1986444218 cites W2170418680 @default.
- W1986444218 cites W2411715887 @default.
- W1986444218 doi "https://doi.org/10.1016/s0006-8993(00)02088-6" @default.
- W1986444218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10799696" @default.
- W1986444218 hasPublicationYear "2000" @default.
- W1986444218 type Work @default.
- W1986444218 sameAs 1986444218 @default.
- W1986444218 citedByCount "9" @default.
- W1986444218 crossrefType "journal-article" @default.
- W1986444218 hasAuthorship W1986444218A5010067320 @default.
- W1986444218 hasAuthorship W1986444218A5027030592 @default.
- W1986444218 hasConcept C126322002 @default.
- W1986444218 hasConcept C178790620 @default.
- W1986444218 hasConcept C185592680 @default.
- W1986444218 hasConcept C2780577055 @default.
- W1986444218 hasConcept C28406088 @default.
- W1986444218 hasConcept C42219234 @default.
- W1986444218 hasConcept C50156730 @default.
- W1986444218 hasConcept C519581460 @default.
- W1986444218 hasConcept C541997718 @default.
- W1986444218 hasConcept C55493867 @default.
- W1986444218 hasConcept C71924100 @default.
- W1986444218 hasConceptScore W1986444218C126322002 @default.
- W1986444218 hasConceptScore W1986444218C178790620 @default.
- W1986444218 hasConceptScore W1986444218C185592680 @default.
- W1986444218 hasConceptScore W1986444218C2780577055 @default.
- W1986444218 hasConceptScore W1986444218C28406088 @default.
- W1986444218 hasConceptScore W1986444218C42219234 @default.
- W1986444218 hasConceptScore W1986444218C50156730 @default.
- W1986444218 hasConceptScore W1986444218C519581460 @default.
- W1986444218 hasConceptScore W1986444218C541997718 @default.
- W1986444218 hasConceptScore W1986444218C55493867 @default.
- W1986444218 hasConceptScore W1986444218C71924100 @default.
- W1986444218 hasIssue "1-2" @default.
- W1986444218 hasLocation W19864442181 @default.
- W1986444218 hasLocation W19864442182 @default.
- W1986444218 hasOpenAccess W1986444218 @default.
- W1986444218 hasPrimaryLocation W19864442181 @default.
- W1986444218 hasRelatedWork W1966543941 @default.
- W1986444218 hasRelatedWork W1973442252 @default.
- W1986444218 hasRelatedWork W1978803387 @default.
- W1986444218 hasRelatedWork W1986444218 @default.
- W1986444218 hasRelatedWork W1996861534 @default.
- W1986444218 hasRelatedWork W2008946021 @default.
- W1986444218 hasRelatedWork W2047687479 @default.
- W1986444218 hasRelatedWork W2074951354 @default.
- W1986444218 hasRelatedWork W2107042299 @default.
- W1986444218 hasRelatedWork W2117676608 @default.
- W1986444218 hasVolume "862" @default.
- W1986444218 isParatext "false" @default.
- W1986444218 isRetracted "false" @default.
- W1986444218 magId "1986444218" @default.
- W1986444218 workType "article" @default.