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• W1986446988 abstract "In addition to two expected pyrazin derivatives, two imidazole analogues of squamocin 1 have been semisynthetised from squamocin derived alpha-ketoesters/alpha-ketoacid, via an unusual condensation-oxidative decarboxylation reaction with 1,2 diamines in presence of acetic acid and oxygen as the key step. Some of these analogues exhibited potent, although significantly reduced cytotoxicities relatively to squamocin 1. In addition, benzimidazole 8 possessed in comparison with the natural acetogenin some interesting cell cycle effects." @default.
• W1986446988 created "2016-06-24" @default.
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• W1986446988 date "2003-08-05" @default.
• W1986446988 modified "2023-09-25" @default.
• W1986446988 title "Semisynthesis of heterocyclic analogues of squamocin, a cytotoxic annonaceous acetogenin, by an unusual oxidative decarboxylation reaction" @default.
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• W1986446988 doi "https://doi.org/10.1016/s0968-0896(03)00306-7" @default.
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