FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986466180> ?p ?o ?g. }

• W1986466180 abstract "Human chorionic somatomammotropin (hCS) and human growth hormone (hGH), despite their different biological activities, show a remarkable degree of homology in their primary structure, which explains their immunological cross-reactivity. On the basis of the hydrophilicity profiles, we predicted that the sequence 165-174 would correspond to an antigenic determinant common to both hormones. The sequence 165-174 was synthesized in the solid phase and the ability to bind antibodies to hCS was tested by a radioimmunoassay at each step of the synthesis, without detaching the peptide from the resin. We found that the immunological sequence able to bind antibodies to hCS is that corresponding to 167-174. In similar experiments, we showed that the sequence 166-174 is able to bind antibodies to hGH. In the plaque-forming cell test using the synthetic fragment 166-174 bound to sheep red blood cells, we also observed that the ratio between the number of cells forming antibodies to hCS and to the 166-174 peptide was always between 0.45 and 0.73, thus suggesting that the 166-174 peptide represents a major determinant of hCS." @default.
• W1986466180 created "2016-06-24" @default.
• W1986466180 creator A5010599118 @default.
• W1986466180 creator A5013827500 @default.
• W1986466180 creator A5028900878 @default.
• W1986466180 creator A5034533889 @default.
• W1986466180 creator A5041676540 @default.
• W1986466180 creator A5043928949 @default.
• W1986466180 creator A5060015026 @default.
• W1986466180 creator A5087309251 @default.
• W1986466180 date "1984-02-01" @default.
• W1986466180 modified "2023-09-27" @default.
• W1986466180 title "Identification and synthesis of an antigenic determinant common to human chorionic somatomammotropin and human growth hormone" @default.
• W1986466180 cites W1542067597 @default.
• W1986466180 cites W1565778121 @default.
• W1986466180 cites W1923918246 @default.
• W1986466180 cites W1973125702 @default.
• W1986466180 cites W1973579608 @default.
• W1986466180 cites W1975304761 @default.
• W1986466180 cites W197781038 @default.
• W1986466180 cites W1988596667 @default.
• W1986466180 cites W1992333741 @default.
• W1986466180 cites W1998236525 @default.
• W1986466180 cites W2002837243 @default.
• W1986466180 cites W2026853898 @default.
• W1986466180 cites W2053418558 @default.
• W1986466180 cites W2059126503 @default.
• W1986466180 cites W2059680068 @default.
• W1986466180 cites W2061117194 @default.
• W1986466180 cites W2061454949 @default.
• W1986466180 cites W2080656627 @default.
• W1986466180 cites W2092720906 @default.
• W1986466180 cites W2137926707 @default.
• W1986466180 cites W2138054962 @default.
• W1986466180 cites W2141155302 @default.
• W1986466180 cites W2146653938 @default.
• W1986466180 cites W2209558968 @default.
• W1986466180 cites W2322616200 @default.
• W1986466180 cites W2333470577 @default.
• W1986466180 cites W2333555214 @default.
• W1986466180 doi "https://doi.org/10.1016/0161-5890(84)90130-5" @default.
• W1986466180 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6200773" @default.
• W1986466180 hasPublicationYear "1984" @default.
• W1986466180 type Work @default.
• W1986466180 sameAs 1986466180 @default.
• W1986466180 citedByCount "16" @default.
• W1986466180 crossrefType "journal-article" @default.
• W1986466180 hasAuthorship W1986466180A5010599118 @default.
• W1986466180 hasAuthorship W1986466180A5013827500 @default.
• W1986466180 hasAuthorship W1986466180A5028900878 @default.
• W1986466180 hasAuthorship W1986466180A5034533889 @default.
• W1986466180 hasAuthorship W1986466180A5041676540 @default.
• W1986466180 hasAuthorship W1986466180A5043928949 @default.
• W1986466180 hasAuthorship W1986466180A5060015026 @default.
• W1986466180 hasAuthorship W1986466180A5087309251 @default.
• W1986466180 hasConcept C104317684 @default.
• W1986466180 hasConcept C147483822 @default.
• W1986466180 hasConcept C153911025 @default.
• W1986466180 hasConcept C159654299 @default.
• W1986466180 hasConcept C165525559 @default.
• W1986466180 hasConcept C167625842 @default.
• W1986466180 hasConcept C176685330 @default.
• W1986466180 hasConcept C185592680 @default.
• W1986466180 hasConcept C195616568 @default.
• W1986466180 hasConcept C203014093 @default.
• W1986466180 hasConcept C2779281246 @default.
• W1986466180 hasConcept C515207424 @default.
• W1986466180 hasConcept C55493867 @default.
• W1986466180 hasConcept C86803240 @default.
• W1986466180 hasConceptScore W1986466180C104317684 @default.
• W1986466180 hasConceptScore W1986466180C147483822 @default.
• W1986466180 hasConceptScore W1986466180C153911025 @default.
• W1986466180 hasConceptScore W1986466180C159654299 @default.
• W1986466180 hasConceptScore W1986466180C165525559 @default.
• W1986466180 hasConceptScore W1986466180C167625842 @default.
• W1986466180 hasConceptScore W1986466180C176685330 @default.
• W1986466180 hasConceptScore W1986466180C185592680 @default.
• W1986466180 hasConceptScore W1986466180C195616568 @default.
• W1986466180 hasConceptScore W1986466180C203014093 @default.
• W1986466180 hasConceptScore W1986466180C2779281246 @default.
• W1986466180 hasConceptScore W1986466180C515207424 @default.
• W1986466180 hasConceptScore W1986466180C55493867 @default.
• W1986466180 hasConceptScore W1986466180C86803240 @default.
• W1986466180 hasLocation W19864661801 @default.
• W1986466180 hasLocation W19864661802 @default.
• W1986466180 hasOpenAccess W1986466180 @default.
• W1986466180 hasPrimaryLocation W19864661801 @default.
• W1986466180 hasRelatedWork W1604248381 @default.
• W1986466180 hasRelatedWork W1872459230 @default.
• W1986466180 hasRelatedWork W1922768394 @default.
• W1986466180 hasRelatedWork W1970680028 @default.
• W1986466180 hasRelatedWork W2071531117 @default.
• W1986466180 hasRelatedWork W2120609186 @default.
• W1986466180 hasRelatedWork W2370691445 @default.
• W1986466180 hasRelatedWork W2417433600 @default.
• W1986466180 hasRelatedWork W2471206582 @default.
• W1986466180 hasRelatedWork W1587311881 @default.
• W1986466180 isParatext "false" @default.
• W1986466180 isRetracted "false" @default.
• W1986466180 magId "1986466180" @default.

• next