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- W1986469716 abstract "To the Editor. —There are no data to indicate that physicians should recommend 30 mL (1 fl oz) of alcohol a day because no data were presented to prove that 30 mL of alcohol a day increases life span. 1 The comment in the accompanying Editorial 2 that 80 924 lives a year would be saved is based on the unsupported conjecture that the J-shaped alcohol mortality curve has a downward drop at 30 mL of alcohol a day. The article refers to two studies that show that acute alcohol intake reduces (not increases) t-PA activity. Physicians cannot recommend that the public take alcohol, which has such a narrow (or nonexistent) therapeutic range. The beneficial effect of alcohol may be the protein malnutrition that is associated with increasing alcohol use. Table 1 of the article should have evaluated protein nutrition (perhaps by doing a serum albumin level correlation with t-PA)" @default.
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- W1986469716 date "1995-05-10" @default.
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- W1986469716 title "Alcohol Consumption and Tissue-Type Plasminogen Activator" @default.
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- W1986469716 doi "https://doi.org/10.1001/jama.1995.03520420028017" @default.
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