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- W1986476739 abstract "Little is known regarding the prognostic implications of exercise myocardial perfusion scans in patients late after myocardial infarction (MI). Thus, we studied 399 patients who underwent rest TI-201/exercise sestamibi SPECT more than one year after MI (mean 9 ± 7, range 2–37 years) who were followed up for more than 1 year (mean follow-up 21 ±6 months). Exercise and rest scans were visually assessed in 20 myocardial segments using a 5 point scale (0 = normal, 4 = no uptake). An infarct zone was defined as a region within a vascular territory with a rest score of > 1. A difference ≥1 between stress and rest scores for a segment was defined as ischemic. All patients were followed up for at least one year after their test. 25 hard events (HE; cardiac death or repeat MI) occurred (6.3% HE rate). A large proportion of patients had ischemia by scan (66%, 263/399) or subendocardial MI (no fixed defects; 44%, 177/399). Patients with ischemia outside an infarct zone (n = 209) and inside an infarct zone (n = 85) both had an event rate of 7%. HE rates were as follows.Empty CellReversible Defects > 26/66 (9%)3/51 (6%)4/53 (7.5%)1–23/31 (10%)0/19 (0%)4/45 (9%)02/80 (2.5%)0/15 (0%)3/39 (8%)Fixed Defects01–2 > 2 There was no difference in HE rates between patients with only large fixed defects and only reversible defects. (1) In patients with temporally remote infarction, the presence of large fixed defects confers high HE rates similar to reversible defects (possibly due to the risks of late infarct remodeling). (2) Ischemia within and outside infarct zones denotes similar high risk for adverse outcomes." @default.
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- W1986476739 date "1995-02-01" @default.
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- W1986476739 title "708-2 Are All Defects Created Equal? Relative Prognostic Implications of Fixed and Reversible Hypoperfusion in Patients with Temporally Remote Myocardial Infarction" @default.
- W1986476739 doi "https://doi.org/10.1016/0735-1097(95)91645-e" @default.
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