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- W1986611432 abstract "Macroscopic jejunal damage and plasma leakage induced within 15 min by E. coli lipopolysaccharide (LPS 50 mg kg−1 i.v.) in the rat was enhanced by the inhibitor of nitric oxide (NO) formation, NG-monomethyl-L-arginine (L-NMMA 50 mg kg−1 i.v.). The nitro-vasodilator, S-nitroso-N-acetyl-pencillamine (SNAP; 10 μg kg−1 min−1 i.v.), which generates NO, attenuated both LPS-induced intestinal damage and the enhancement of such damage and plasma leakage produced by L-NMMA. Endogenous NO may thus have a protective role in the intestinal vasculature that can be mimicked by generators of NO." @default.
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- W1986611432 date "1990-12-01" @default.
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- W1986611432 title "Protective effect of S-nitroso-N-acetyl-penicillamine in endotoxin-induced acute intestinal damage in the rat" @default.
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- W1986611432 doi "https://doi.org/10.1016/0014-2999(90)94185-z" @default.
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