Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986620734> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1986620734 endingPage "177" @default.
- W1986620734 startingPage "165" @default.
- W1986620734 abstract "The 63-kDa antigen recognized by the monoclonal antibody F7D6 is present in all Drosophila embryonic cells and disappears from most tissues as each one reaches its final, differentiated state. Larval tissues lose the antigen around the time of hatching, imaginal tissues lose it during metamorphosis, and germ cells lose it during gametogenesis (Bedian et al: Devel Biol 115:105–118, 1986). The nervous system and spontaneously contracting musculature of the gut and gonads are exceptions and remain antigen positive at all stages. The F7D6 antigen appears to be associated with dividing, undifferentiated cells and electrogenic cells. This prompted us to test tumors for antigen presence. We tested four different recessive mutants that give rise to four different types of tumorous transformation: the embryonic tumor Notch, several larval melanotic tumors, the imaginal disc tumor 1(2)gl, and three alleles of the ovarian tumor otu. In all cases, tumorous tissues in homozygotes contained the F7D6 antigen. The electrophoretic mobility of the antigen appeared to be unaltered in tumorous tissues compared to normal cells, but the antigen is expressed at higher levels. The antigen is found on the cytoplasmic surface of plasma membranes and appears to be a marker of undifferentiated normal and tumorous cells. Similarities and differences between the F7D6 antigen and Drosophila c-src protein are discussed." @default.
- W1986620734 created "2016-06-24" @default.
- W1986620734 creator A5014557125 @default.
- W1986620734 creator A5023227097 @default.
- W1986620734 date "1987-01-01" @default.
- W1986620734 modified "2023-10-16" @default.
- W1986620734 title "Expression of the differentiation antigen F7D6 in tumorous tissues ofDrosophila" @default.
- W1986620734 cites W113109715 @default.
- W1986620734 cites W127802410 @default.
- W1986620734 cites W1557757273 @default.
- W1986620734 cites W1771400236 @default.
- W1986620734 cites W1775749144 @default.
- W1986620734 cites W1968911057 @default.
- W1986620734 cites W1980223495 @default.
- W1986620734 cites W1986114497 @default.
- W1986620734 cites W1989765568 @default.
- W1986620734 cites W1999728118 @default.
- W1986620734 cites W2001743581 @default.
- W1986620734 cites W2021570486 @default.
- W1986620734 cites W2043932127 @default.
- W1986620734 cites W2055484995 @default.
- W1986620734 cites W2058815469 @default.
- W1986620734 cites W2064529356 @default.
- W1986620734 cites W2071532423 @default.
- W1986620734 cites W2073151030 @default.
- W1986620734 cites W2081059129 @default.
- W1986620734 cites W2090992046 @default.
- W1986620734 cites W2092616984 @default.
- W1986620734 cites W2139948799 @default.
- W1986620734 cites W2158343596 @default.
- W1986620734 cites W4249117825 @default.
- W1986620734 doi "https://doi.org/10.1002/dvg.1020080305" @default.
- W1986620734 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3502971" @default.
- W1986620734 hasPublicationYear "1987" @default.
- W1986620734 type Work @default.
- W1986620734 sameAs 1986620734 @default.
- W1986620734 citedByCount "3" @default.
- W1986620734 crossrefType "journal-article" @default.
- W1986620734 hasAuthorship W1986620734A5014557125 @default.
- W1986620734 hasAuthorship W1986620734A5023227097 @default.
- W1986620734 hasConcept C104317684 @default.
- W1986620734 hasConcept C147483822 @default.
- W1986620734 hasConcept C153911025 @default.
- W1986620734 hasConcept C159654299 @default.
- W1986620734 hasConcept C190062978 @default.
- W1986620734 hasConcept C203014093 @default.
- W1986620734 hasConcept C2780104201 @default.
- W1986620734 hasConcept C542903549 @default.
- W1986620734 hasConcept C54355233 @default.
- W1986620734 hasConcept C86803240 @default.
- W1986620734 hasConcept C91986751 @default.
- W1986620734 hasConcept C95444343 @default.
- W1986620734 hasConceptScore W1986620734C104317684 @default.
- W1986620734 hasConceptScore W1986620734C147483822 @default.
- W1986620734 hasConceptScore W1986620734C153911025 @default.
- W1986620734 hasConceptScore W1986620734C159654299 @default.
- W1986620734 hasConceptScore W1986620734C190062978 @default.
- W1986620734 hasConceptScore W1986620734C203014093 @default.
- W1986620734 hasConceptScore W1986620734C2780104201 @default.
- W1986620734 hasConceptScore W1986620734C542903549 @default.
- W1986620734 hasConceptScore W1986620734C54355233 @default.
- W1986620734 hasConceptScore W1986620734C86803240 @default.
- W1986620734 hasConceptScore W1986620734C91986751 @default.
- W1986620734 hasConceptScore W1986620734C95444343 @default.
- W1986620734 hasIssue "3" @default.
- W1986620734 hasLocation W19866207341 @default.
- W1986620734 hasLocation W19866207342 @default.
- W1986620734 hasOpenAccess W1986620734 @default.
- W1986620734 hasPrimaryLocation W19866207341 @default.
- W1986620734 hasRelatedWork W1602847563 @default.
- W1986620734 hasRelatedWork W1973692620 @default.
- W1986620734 hasRelatedWork W1997716688 @default.
- W1986620734 hasRelatedWork W2038126255 @default.
- W1986620734 hasRelatedWork W2063428357 @default.
- W1986620734 hasRelatedWork W2064089409 @default.
- W1986620734 hasRelatedWork W2073262237 @default.
- W1986620734 hasRelatedWork W2159606738 @default.
- W1986620734 hasRelatedWork W2368460920 @default.
- W1986620734 hasRelatedWork W2380360044 @default.
- W1986620734 hasVolume "8" @default.
- W1986620734 isParatext "false" @default.
- W1986620734 isRetracted "false" @default.
- W1986620734 magId "1986620734" @default.
- W1986620734 workType "article" @default.