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• W1986677154 abstract "The linker histone subtype H1.1 belongs to the group of main-type histones and is synthesized in somatic tissues as well as in germ cells during the S phase of the cell cycle. In adult mice the histone gene H1.1 is expressed mainly in thymus, spleen, and testis. The single-copy gene coding for the H1.1 protein was eliminated by homologous recombination in mouse embryonic stem cells. Mice homozygous for the deficient H1.1 gene developed normally until the adult stage without H1.1 mRNA and H1.1 protein. No anatomic abnormalities could be detected. In addition, mice lacking the H1.1 gene were fertile and they showed normal spermatogenesis and testicular morphology." @default.
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• W1986677154 date "2000-02-01" @default.
• W1986677154 modified "2023-09-27" @default.
• W1986677154 title "Spermatogenesis in Mice Is Not Affected by Histone H1.1 Deficiency" @default.
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• W1986677154 doi "https://doi.org/10.1006/excr.1999.4767" @default.
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