Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986687183> ?p ?o ?g. }
- W1986687183 abstract "The importance of regulatory T cells (Tregs) in balancing the effector arm of the immune system is well documented, playing a central role in preventing autoimmunity, facilitating graft tolerance following organ transplantation, and having a detrimental impact on the development of anti-tumor immunity. These regulatory responses use a variety of mechanisms to mediate suppression, including soluble factors. While IL-10 and TGF-β are the most commonly studied immunosuppressive cytokines, the recently identified IL-35 has been shown to have potent suppressive function in vitro and in vivo. Furthermore, not only does IL-35 have the ability to directly suppress effector T cell responses, it is also able to expand regulatory responses by propagating infectious tolerance and generating a potent population of IL-35-expressing inducible Tregs. In this review, we summarize research characterizing the structure and function of IL-35, examine its role in disease, and discuss how it can contribute to the induction of a distinct population of inducible Tregs." @default.
- W1986687183 created "2016-06-24" @default.
- W1986687183 creator A5008871183 @default.
- W1986687183 creator A5025535317 @default.
- W1986687183 creator A5091502681 @default.
- W1986687183 date "2013-01-01" @default.
- W1986687183 modified "2023-10-01" @default.
- W1986687183 title "Interleukin 35: A Key Mediator of Suppression and the Propagation of Infectious Tolerance" @default.
- W1986687183 cites W1486822318 @default.
- W1986687183 cites W1526112396 @default.
- W1986687183 cites W1527526213 @default.
- W1986687183 cites W1552885427 @default.
- W1986687183 cites W1567420244 @default.
- W1986687183 cites W1574254013 @default.
- W1986687183 cites W1585462612 @default.
- W1986687183 cites W1691370130 @default.
- W1986687183 cites W1754891924 @default.
- W1986687183 cites W1850727658 @default.
- W1986687183 cites W1966922635 @default.
- W1986687183 cites W1968786539 @default.
- W1986687183 cites W1970188825 @default.
- W1986687183 cites W1977165060 @default.
- W1986687183 cites W1985445357 @default.
- W1986687183 cites W1988637973 @default.
- W1986687183 cites W1990227965 @default.
- W1986687183 cites W1991746123 @default.
- W1986687183 cites W1994575657 @default.
- W1986687183 cites W1996087599 @default.
- W1986687183 cites W2006741811 @default.
- W1986687183 cites W2009219530 @default.
- W1986687183 cites W2013010265 @default.
- W1986687183 cites W2021928123 @default.
- W1986687183 cites W2022025787 @default.
- W1986687183 cites W2022632065 @default.
- W1986687183 cites W2039513919 @default.
- W1986687183 cites W2048014578 @default.
- W1986687183 cites W2048708042 @default.
- W1986687183 cites W2056138805 @default.
- W1986687183 cites W2058428161 @default.
- W1986687183 cites W2062461507 @default.
- W1986687183 cites W2068238618 @default.
- W1986687183 cites W2070213858 @default.
- W1986687183 cites W2074632761 @default.
- W1986687183 cites W2078647306 @default.
- W1986687183 cites W2080092936 @default.
- W1986687183 cites W2089912584 @default.
- W1986687183 cites W2095532895 @default.
- W1986687183 cites W2097762449 @default.
- W1986687183 cites W2100474263 @default.
- W1986687183 cites W2101195992 @default.
- W1986687183 cites W2102857641 @default.
- W1986687183 cites W2104981376 @default.
- W1986687183 cites W2106684817 @default.
- W1986687183 cites W2106910404 @default.
- W1986687183 cites W2109023646 @default.
- W1986687183 cites W2110277103 @default.
- W1986687183 cites W2111049347 @default.
- W1986687183 cites W2111585885 @default.
- W1986687183 cites W2118134207 @default.
- W1986687183 cites W2119091751 @default.
- W1986687183 cites W2121221609 @default.
- W1986687183 cites W2125742006 @default.
- W1986687183 cites W2126486145 @default.
- W1986687183 cites W2127022334 @default.
- W1986687183 cites W2127858962 @default.
- W1986687183 cites W2137351522 @default.
- W1986687183 cites W2137407243 @default.
- W1986687183 cites W2139621564 @default.
- W1986687183 cites W2147332068 @default.
- W1986687183 cites W2148592593 @default.
- W1986687183 cites W2149022536 @default.
- W1986687183 cites W2149200785 @default.
- W1986687183 cites W2162204705 @default.
- W1986687183 cites W2166153412 @default.
- W1986687183 cites W2167849861 @default.
- W1986687183 doi "https://doi.org/10.3389/fimmu.2013.00315" @default.
- W1986687183 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3798782" @default.
- W1986687183 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24151492" @default.
- W1986687183 hasPublicationYear "2013" @default.
- W1986687183 type Work @default.
- W1986687183 sameAs 1986687183 @default.
- W1986687183 citedByCount "109" @default.
- W1986687183 countsByYear W19866871832014 @default.
- W1986687183 countsByYear W19866871832015 @default.
- W1986687183 countsByYear W19866871832016 @default.
- W1986687183 countsByYear W19866871832017 @default.
- W1986687183 countsByYear W19866871832018 @default.
- W1986687183 countsByYear W19866871832019 @default.
- W1986687183 countsByYear W19866871832020 @default.
- W1986687183 countsByYear W19866871832021 @default.
- W1986687183 countsByYear W19866871832022 @default.
- W1986687183 countsByYear W19866871832023 @default.
- W1986687183 crossrefType "journal-article" @default.
- W1986687183 hasAuthorship W1986687183A5008871183 @default.
- W1986687183 hasAuthorship W1986687183A5025535317 @default.
- W1986687183 hasAuthorship W1986687183A5091502681 @default.
- W1986687183 hasBestOaLocation W19866871831 @default.
- W1986687183 hasConcept C104317684 @default.
- W1986687183 hasConcept C14036430 @default.
- W1986687183 hasConcept C203014093 @default.