Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986742021> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W1986742021 endingPage "142" @default.
- W1986742021 startingPage "135" @default.
- W1986742021 abstract "The mechanical and hemodynamic components of a cardiogenic hypertensive chemoreflex were studied in 50 dogs. Within 6 seconds after a single injection of serotonin (100 microgram/ml) into the left atrium, mean pressure (mm Hg) rose in the aorta from 103 to 197 and in the pulmonary artery from 21 to 34. Left ventricular dp/dt virtually doubled. There was an increase (75%) in peripheral vascular resistance that returned to control within 10 seconds. There was no significant change in pulmonary vascular resistance. Aortic and pulmonary arterial hypertension were associated with a profound depression (82%) in atrial force. Atropine transformed this negative inotropic effect on the atria into a positive inotropic action that averaged 65%. In contrast, ventricular force was always sharply increased, more in the right (95%) than in the left ventricle (50%). Bilateral stellectomy did not eliminate the reflex but it completely abolished the initial increase of cardiac contractility; a delayed increase in contractility persisted and was due exclusively to release of catecholamines from the adrenal glands. This cardiogenic hypertensive chemoreflex uses the vagus for its afferent neural traffic and both the sympathetic and the vagus nerves for its efferent route. The brief and intense systemic vasoconstriction concomitant with an increase in cardiac contractility might represent a kind of aortic cough. Some possible clinical implications are discussed." @default.
- W1986742021 created "2016-06-24" @default.
- W1986742021 creator A5023047243 @default.
- W1986742021 creator A5057805009 @default.
- W1986742021 creator A5067010921 @default.
- W1986742021 date "1978-01-01" @default.
- W1986742021 modified "2023-09-26" @default.
- W1986742021 title "Hemodynamic components of a cardiogenic hypertensive chemoreflex in dogs." @default.
- W1986742021 cites W1991181037 @default.
- W1986742021 cites W2016348280 @default.
- W1986742021 cites W2037104307 @default.
- W1986742021 cites W2042314767 @default.
- W1986742021 cites W2049294034 @default.
- W1986742021 cites W2068062923 @default.
- W1986742021 cites W2090710052 @default.
- W1986742021 cites W2165972434 @default.
- W1986742021 cites W2407071702 @default.
- W1986742021 doi "https://doi.org/10.1161/01.res.42.1.135" @default.
- W1986742021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/618594" @default.
- W1986742021 hasPublicationYear "1978" @default.
- W1986742021 type Work @default.
- W1986742021 sameAs 1986742021 @default.
- W1986742021 citedByCount "20" @default.
- W1986742021 crossrefType "journal-article" @default.
- W1986742021 hasAuthorship W1986742021A5023047243 @default.
- W1986742021 hasAuthorship W1986742021A5057805009 @default.
- W1986742021 hasAuthorship W1986742021A5067010921 @default.
- W1986742021 hasBestOaLocation W19867420211 @default.
- W1986742021 hasConcept C126322002 @default.
- W1986742021 hasConcept C139940330 @default.
- W1986742021 hasConcept C155710745 @default.
- W1986742021 hasConcept C164705383 @default.
- W1986742021 hasConcept C178853913 @default.
- W1986742021 hasConcept C2778921608 @default.
- W1986742021 hasConcept C2779980429 @default.
- W1986742021 hasConcept C2780940725 @default.
- W1986742021 hasConcept C39133596 @default.
- W1986742021 hasConcept C42219234 @default.
- W1986742021 hasConcept C58245268 @default.
- W1986742021 hasConcept C71924100 @default.
- W1986742021 hasConceptScore W1986742021C126322002 @default.
- W1986742021 hasConceptScore W1986742021C139940330 @default.
- W1986742021 hasConceptScore W1986742021C155710745 @default.
- W1986742021 hasConceptScore W1986742021C164705383 @default.
- W1986742021 hasConceptScore W1986742021C178853913 @default.
- W1986742021 hasConceptScore W1986742021C2778921608 @default.
- W1986742021 hasConceptScore W1986742021C2779980429 @default.
- W1986742021 hasConceptScore W1986742021C2780940725 @default.
- W1986742021 hasConceptScore W1986742021C39133596 @default.
- W1986742021 hasConceptScore W1986742021C42219234 @default.
- W1986742021 hasConceptScore W1986742021C58245268 @default.
- W1986742021 hasConceptScore W1986742021C71924100 @default.
- W1986742021 hasIssue "1" @default.
- W1986742021 hasLocation W19867420211 @default.
- W1986742021 hasLocation W19867420212 @default.
- W1986742021 hasOpenAccess W1986742021 @default.
- W1986742021 hasPrimaryLocation W19867420211 @default.
- W1986742021 hasRelatedWork W2030432546 @default.
- W1986742021 hasRelatedWork W2073819811 @default.
- W1986742021 hasRelatedWork W2075932017 @default.
- W1986742021 hasRelatedWork W2348533365 @default.
- W1986742021 hasRelatedWork W2399310367 @default.
- W1986742021 hasRelatedWork W2400525383 @default.
- W1986742021 hasRelatedWork W2407288316 @default.
- W1986742021 hasRelatedWork W2436547916 @default.
- W1986742021 hasRelatedWork W2475327391 @default.
- W1986742021 hasRelatedWork W2136750338 @default.
- W1986742021 hasVolume "42" @default.
- W1986742021 isParatext "false" @default.
- W1986742021 isRetracted "false" @default.
- W1986742021 magId "1986742021" @default.
- W1986742021 workType "article" @default.