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- W1986749081 abstract "We describe a new approach to building up the head-groups of synthetic phospholipids. The approach is based upon the construction first of a completely neutral head-group, in which the phosphate bears three neutral alkyl substituents. One of these is the glycerol residue, and the second is a methyl group, which is removed cleanly at a later stage. The third determines the identity of the phospholipid to be synthesized: the range of phospholipids obtainable in this manner is very wide, and includes phosphatidylserine and phosphatidylglycerol. High-yield syntheses of these two lipids are presented here for the first time. In addition, we describe for the first time the synthesis of a potentially valuable serine-bearing precursor, N-BOC-serine t-butyl ester (BOC = t-butoxy carbonyl)." @default.
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- W1986749081 date "1988-05-01" @default.
- W1986749081 modified "2023-09-29" @default.
- W1986749081 title "Synthesis of enantiomerically pure phospholipids including phosphatidylserine and phosphatidylglycerol" @default.
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- W1986749081 doi "https://doi.org/10.1016/0009-3084(88)90032-1" @default.
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