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- W1986755071 abstract "A simple three-step synthesis of the potent arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) has been developed. The key step was alkylation of the NiII complex of the Schiff base derived from glycine and (S)-2-[N‘-(N-benzylprolyl)amino]benzophenone (BPB) with pinacol 4-bromobutylboronate. Acidic hydrolysis afforded ABH in 50% overall yield, high enantiomeric excess, and quantitative recovery of the chiral auxiliary." @default.
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- W1986755071 date "2005-09-01" @default.
- W1986755071 modified "2023-10-09" @default.
- W1986755071 title "Improved and High Yield Synthesis of the Potent Arginase Inhibitor: 2(<i>S</i>)-Amino-6-boronohexanoic Acid" @default.
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- W1986755071 doi "https://doi.org/10.1021/op050096n" @default.
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