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- W1986775431 abstract "In order to study qualitative differences in effectiveness between radiation of low LET and of high LET on human tumours in vivo, results from 147 cases of bronchial carcinoma which as a control series had been irradiated with telecobalt therapy only, have been compared with results from a series of 20 cases receiving as part of their treatment, cyclotron produced neutrons in a proportion of the total dose of 20% and with results from 15 cases receiving a 35% proportion of neutrons. A common standard was employed by histological examination of all cases (autopsy findings and surgical specimens) for surviving tumour rests. Smaller control series of oesophagus and gastric carcinomata were studied in the same way. All series exhibited a distinctly stronger effectiveness of the combined irradiations with neutrons and gamma rays, which for the bronchial carcinomata treated with a 35% proportion of neutrons was confirmed statistically. The statistical evaluation of the comparability of the series (tumour size, total aose, total irradiation time, histological tumour types) corroborated the findings concerning the qualitatively higher neutron effectiveness in all respects. The difference in sequences of the irradiation, i.e. N-γ or γ-N, as well as the length of the intervals did not cause observable changes in effectiveness." @default.
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- W1986775431 date "1974-06-01" @default.
- W1986775431 modified "2023-09-25" @default.
- W1986775431 title "Comparison between neutron therapy and 60Co gamma ray therapy of bronchial, gastric and oesophagus carcinomata" @default.
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- W1986775431 doi "https://doi.org/10.1016/0014-2964(74)90200-x" @default.
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