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- W1986779631 abstract "Antibodies reactive with human erythropoietin were isolated from the serum of rabbits immunized with a twenty-six amino acid synthetic polypeptide corresponding to a proposed NH2-terminal sequence of the hormone. As shown by inhibition with peptide fragments, those antibodies that bound to erythropoietin recognized the (8–15) domain, strongly suggesting that this region is exposed on the hormone's surface. This was confirmed by affinity purification of these antibodies on immobilized fragment (8–15). These results provide insight into the tertiary structure of human erythropoietin and suggest uses for the sequence-specific antibodies in labeling the hormone." @default.
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- W1986779631 date "1985-06-01" @default.
- W1986779631 modified "2023-09-25" @default.
- W1986779631 title "Identification of a surface epitope of human erythropoietin with anti-peptide antibodies" @default.
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- W1986779631 doi "https://doi.org/10.1016/0006-291x(85)91949-7" @default.
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