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- W1986803558 abstract "Honeybees have been studied for centuries, starting with Aristotle, who wrote the first book about bee breeding. More than 2000 years later, the honeybee entered the genomic era as the first social insect whose genome was sequenced, leading to significant insight into the molecular mechanisms underlying social behavior. In addition, gene expression studies and knockdown using RNAi have extended the understanding of social interactions. Much of the work has focused on caste determination – the mechanism that results in reproductive division of labor, division of labor within the worker caste, and worker reproduction – an essential process underlying eusociality. Here we review the molecular factors involved in caste determination and the differential regulation of caste-specific genes. Recent findings suggest that division of labor is influenced by a small number of loci showing high levels of pleiotropy, suggesting that changes in a small number of genes lead to large changes in the phenotype." @default.
- W1986803558 created "2016-06-24" @default.
- W1986803558 creator A5059064563 @default.
- W1986803558 creator A5074714224 @default.
- W1986803558 date "2013-11-01" @default.
- W1986803558 modified "2023-10-14" @default.
- W1986803558 title "Genetic underpinnings of division of labor in the honeybee (Apis mellifera)" @default.
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- W1986803558 doi "https://doi.org/10.1016/j.tig.2013.08.002" @default.
- W1986803558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24012355" @default.
- W1986803558 hasPublicationYear "2013" @default.
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