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- W1986803855 abstract "The ϵ-(γ-glutamic)lysine bond is a covalent interaction which has been found to crosslink polypeptide chains of a number of extracellular proteins. Among known covalent bonds crosslinking protein chains, it is unique in that it is formed directly by enzymatic catalysis, a property which may also endow Glu-Lys crosslink formation with important intracellular functions. We found glutamic-lysine bonds to be present in the procaryote, Escherichia coli , in primitive eucaryotes such as the slime mold, Physarum polycephalum , and the ciliate, Paramecium aurelia , and in muscle cells of a bird and a mammal. Our data show that, although Glu-Lys bonds occur in low concentrations in cellular proteins, they are nevertheless widely distributed. Evidence is also presented indicating that the low levels of the Glu-Lys bonds we measure in the proteins of various cells types are not artifacts of our analytical procedures." @default.
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- W1986803855 date "1979-02-01" @default.
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- W1986803855 title "Presence of the ϵ-(γ-glutamic)lysine crosslink in cellular proteins" @default.
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- W1986803855 doi "https://doi.org/10.1016/0005-2795(79)90401-x" @default.
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