FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986865676> ?p ?o ?g. }

• W1986865676 endingPage "955" @default.
• W1986865676 startingPage "949" @default.
• W1986865676 abstract "The importance of subclassifying pulmonary nonsmall cell carcinoma (NSCLC) in cytologic material is becoming increasingly paramount. Occasionally, cell blocks traditionally used for ancillary studies are sparsely cellular or acellular. Hence, we investigated the diagnostic utility of immunocytochemistry for Napsin-A, TTF-1, and p63 on direct smears of NSCLC. Immunohistochemistry for Napsin-A was initially tested on a tissue microarray (TMA) composed of pulmonary adenocarcinoma. Subsequently, in 25 cases, immunocytochemistry for Napsin-A, TTF-1, and p63 was performed on cytologic direct smears. Smears were prepared from tumor cells scraped from lung resection specimens (n = 10), endobronchial ultrasound-guided transbronchial fine-needle aspirates (n = 13), and pelleted cell material from pleural effusions (n = 2). Immunohistochemistry utilizing the TMA revealed Napsin-A positivity in 73% of pulmonary ADCs. Next, immunocytochemistry on direct cytologic smears demonstrated a Napsin-A(+)/TTF-1(+) immunophenotype in 15 of 18 adenocarcinomas; p63 was completely negative (n = 12) or only focally positive (n = 3) in these 15 adenocarcinomas. The remaining three adenocarcinomas were negative for all three markers. All six squamous cell carcinomas were Napsin-A(−)/TTF-1(−) and diffusely p63(+). In conclusion, direct smears represent a feasible and robust source of cellular material for immunocytochemical studies to diagnose pulmonary ADC and SQC. Our method allows the cytologist to confirm on site that material for diagnostic immunocytochemistry is present thereby serving as a safeguard in instances where the cell block is of insufficient cellularity. Diagn. Cytopathol. 2012. © 2011 Wiley Periodicals, Inc." @default.
• W1986865676 created "2016-06-24" @default.
• W1986865676 creator A5000651180 @default.
• W1986865676 creator A5011351564 @default.
• W1986865676 creator A5013199827 @default.
• W1986865676 creator A5046728026 @default.
• W1986865676 creator A5049591603 @default.
• W1986865676 creator A5062802224 @default.
• W1986865676 creator A5069961747 @default.
• W1986865676 creator A5074991634 @default.
• W1986865676 date "2011-04-15" @default.
• W1986865676 modified "2023-10-07" @default.
• W1986865676 title "The application and diagnostic utility of immunocytochemistry on direct smears in the diagnosis of pulmonary adenocarcinoma and squamous cell carcinoma" @default.
• W1986865676 cites W1967985864 @default.
• W1986865676 cites W1969376370 @default.
• W1986865676 cites W1973414121 @default.
• W1986865676 cites W1996804310 @default.
• W1986865676 cites W2010770530 @default.
• W1986865676 cites W2013733453 @default.
• W1986865676 cites W2017214085 @default.
• W1986865676 cites W2020371210 @default.
• W1986865676 cites W2022664102 @default.
• W1986865676 cites W2038602639 @default.
• W1986865676 cites W2066500467 @default.
• W1986865676 cites W2074657801 @default.
• W1986865676 cites W2084845277 @default.
• W1986865676 cites W2099725888 @default.
• W1986865676 cites W2100785570 @default.
• W1986865676 cites W2101692676 @default.
• W1986865676 cites W2109373031 @default.
• W1986865676 cites W2125212831 @default.
• W1986865676 cites W2168082935 @default.
• W1986865676 cites W4234756084 @default.
• W1986865676 cites W4242948142 @default.
• W1986865676 doi "https://doi.org/10.1002/dc.21680" @default.
• W1986865676 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21500373" @default.
• W1986865676 hasPublicationYear "2011" @default.
• W1986865676 type Work @default.
• W1986865676 sameAs 1986865676 @default.
• W1986865676 citedByCount "27" @default.
• W1986865676 countsByYear W19868656762012 @default.
• W1986865676 countsByYear W19868656762013 @default.
• W1986865676 countsByYear W19868656762014 @default.
• W1986865676 countsByYear W19868656762015 @default.
• W1986865676 countsByYear W19868656762016 @default.
• W1986865676 countsByYear W19868656762019 @default.
• W1986865676 countsByYear W19868656762020 @default.
• W1986865676 countsByYear W19868656762021 @default.
• W1986865676 countsByYear W19868656762022 @default.
• W1986865676 countsByYear W19868656762023 @default.
• W1986865676 crossrefType "journal-article" @default.
• W1986865676 hasAuthorship W1986865676A5000651180 @default.
• W1986865676 hasAuthorship W1986865676A5011351564 @default.
• W1986865676 hasAuthorship W1986865676A5013199827 @default.
• W1986865676 hasAuthorship W1986865676A5046728026 @default.
• W1986865676 hasAuthorship W1986865676A5049591603 @default.
• W1986865676 hasAuthorship W1986865676A5062802224 @default.
• W1986865676 hasAuthorship W1986865676A5069961747 @default.
• W1986865676 hasAuthorship W1986865676A5074991634 @default.
• W1986865676 hasBestOaLocation W19868656762 @default.
• W1986865676 hasConcept C121608353 @default.
• W1986865676 hasConcept C126322002 @default.
• W1986865676 hasConcept C142724271 @default.
• W1986865676 hasConcept C18823058 @default.
• W1986865676 hasConcept C193270364 @default.
• W1986865676 hasConcept C204232928 @default.
• W1986865676 hasConcept C2775934546 @default.
• W1986865676 hasConcept C2776170712 @default.
• W1986865676 hasConcept C2777546739 @default.
• W1986865676 hasConcept C2777714996 @default.
• W1986865676 hasConcept C2778654104 @default.
• W1986865676 hasConcept C2781182431 @default.
• W1986865676 hasConcept C3019992690 @default.
• W1986865676 hasConcept C35866371 @default.
• W1986865676 hasConcept C71924100 @default.
• W1986865676 hasConceptScore W1986865676C121608353 @default.
• W1986865676 hasConceptScore W1986865676C126322002 @default.
• W1986865676 hasConceptScore W1986865676C142724271 @default.
• W1986865676 hasConceptScore W1986865676C18823058 @default.
• W1986865676 hasConceptScore W1986865676C193270364 @default.
• W1986865676 hasConceptScore W1986865676C204232928 @default.
• W1986865676 hasConceptScore W1986865676C2775934546 @default.
• W1986865676 hasConceptScore W1986865676C2776170712 @default.
• W1986865676 hasConceptScore W1986865676C2777546739 @default.
• W1986865676 hasConceptScore W1986865676C2777714996 @default.
• W1986865676 hasConceptScore W1986865676C2778654104 @default.
• W1986865676 hasConceptScore W1986865676C2781182431 @default.
• W1986865676 hasConceptScore W1986865676C3019992690 @default.
• W1986865676 hasConceptScore W1986865676C35866371 @default.
• W1986865676 hasConceptScore W1986865676C71924100 @default.
• W1986865676 hasIssue "11" @default.
• W1986865676 hasLocation W19868656761 @default.
• W1986865676 hasLocation W19868656762 @default.
• W1986865676 hasLocation W19868656763 @default.
• W1986865676 hasLocation W19868656764 @default.
• W1986865676 hasOpenAccess W1986865676 @default.
• W1986865676 hasPrimaryLocation W19868656761 @default.
• W1986865676 hasRelatedWork W1965937080 @default.

• next