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- W1986881224 abstract "Ovarian hyperstimulation syndrome (OHSS) affects 5% of IVF cycles and incurs a 100-fold increase in risk of venous thrombosis over natural conceptions. Identification of women at risk of OHSS can be achieved using antral follicle count (AFC) and anti-Müllerian hormone (AMH). For those women with a high AFC or AMH combining a GnRH antagonist with a conventional hCG trigger will reduce the risk of OHSS and still allow a fresh transfer to occur. Complete abolition of OHSS is however now a reality by avoiding exposure to exogenous hCG. This can be achieved by segmentation of the IVF cycle using a GnRH agonist for final oocyte maturation and then freezing all oocytes or embryos with subsequent replacement of a single embryo in the context of a frozen embryo transfer. This novel approach will ensure a VTE risk equivalent to natural conception and can be combined with conventional thromboprophylaxis strategies." @default.
- W1986881224 created "2016-06-24" @default.
- W1986881224 creator A5020022959 @default.
- W1986881224 date "2013-01-01" @default.
- W1986881224 modified "2023-09-25" @default.
- W1986881224 title "Venous thrombosis during assisted reproduction: Novel risk reduction strategies" @default.
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- W1986881224 doi "https://doi.org/10.1016/s0049-3848(13)00023-6" @default.
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