FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986890775> ?p ?o ?g. }

• W1986890775 endingPage "38" @default.
• W1986890775 startingPage "31" @default.
• W1986890775 abstract "We investigated the effects of sevoflurane (0.7 to 3.6 vol%) on inotropy and lusitropy in left ventricular papillary muscles of healthy hamsters and genetically induced cardiomyopathic (strain BIO 14.6) hamsters in vitro (29 degrees C, pH 7.40, Ca(2+) 2.5 mM, stimulation frequency three per minute) under low (isotony) and high (isometry) loads. Sevoflurane induced a moderate positive inotropic effect in healthy hamsters (maximum unloaded shortening velocity and isometric active force at 3.6 vol%: 115% +/- 12% and 128% +/- 21% of baseline values, respectively; P < 0.01) and in cardiomyopathic hamsters (maximum unloaded shortening velocity and isometric active force at 3.6 vol%: 115% +/- 20% and 124% +/- 31% of baseline values, respectively; P < 0.05). This positive inotropic effect did not differ between healthy and cardiomyopathic hamsters, even when sevoflurane concentrations were corrected for minimum alveolar anesthetic concentration values in each strain, and was unchanged after alpha- and beta-adrenoceptor blockade. After calcium-channel blockade, this positive inotropic effect was abolished in healthy hamsters but enhanced in cardiomyopathic hamsters. In both strains, sevoflurane induced a moderate negative lusitropic effect under low and high loads.A paradoxical moderate positive inotropic effect of sevoflurane was observed in hamster ventricular muscle. This effect was likely related to calcium channel interaction, because after calcium-channel blockade, it was abolished in healthy hamsters and enhanced in cardiomyopathic hamsters." @default.
• W1986890775 created "2016-06-24" @default.
• W1986890775 creator A5044444886 @default.
• W1986890775 creator A5051176970 @default.
• W1986890775 creator A5060653575 @default.
• W1986890775 creator A5066533363 @default.
• W1986890775 creator A5067692511 @default.
• W1986890775 creator A5079234910 @default.
• W1986890775 creator A5079794318 @default.
• W1986890775 date "2002-07-01" @default.
• W1986890775 modified "2023-09-25" @default.
• W1986890775 title "The Paradoxical Positive Inotropic Effect of Sevoflurane in Healthy and Cardiomyopathic Hamsters" @default.
• W1986890775 cites W1964847016 @default.
• W1986890775 cites W1970605370 @default.
• W1986890775 cites W1974210961 @default.
• W1986890775 cites W1977487371 @default.
• W1986890775 cites W1981593087 @default.
• W1986890775 cites W1987762277 @default.
• W1986890775 cites W1988021752 @default.
• W1986890775 cites W1988025716 @default.
• W1986890775 cites W1989810511 @default.
• W1986890775 cites W1992609614 @default.
• W1986890775 cites W2003893395 @default.
• W1986890775 cites W2009715726 @default.
• W1986890775 cites W2012721602 @default.
• W1986890775 cites W2027261121 @default.
• W1986890775 cites W2031955586 @default.
• W1986890775 cites W2034444553 @default.
• W1986890775 cites W2034511355 @default.
• W1986890775 cites W2039682040 @default.
• W1986890775 cites W2040622954 @default.
• W1986890775 cites W2047261089 @default.
• W1986890775 cites W2062278879 @default.
• W1986890775 cites W2062643493 @default.
• W1986890775 cites W2068189750 @default.
• W1986890775 cites W2077201627 @default.
• W1986890775 cites W2087855425 @default.
• W1986890775 cites W2101931124 @default.
• W1986890775 cites W2113052562 @default.
• W1986890775 cites W2147446631 @default.
• W1986890775 cites W2151615819 @default.
• W1986890775 cites W2157557532 @default.
• W1986890775 cites W2159329983 @default.
• W1986890775 cites W2214199416 @default.
• W1986890775 cites W4233419263 @default.
• W1986890775 cites W4238696874 @default.
• W1986890775 cites W4245524109 @default.
• W1986890775 cites W4322697581 @default.
• W1986890775 doi "https://doi.org/10.1097/00000539-200207000-00005" @default.
• W1986890775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12088938" @default.
• W1986890775 hasPublicationYear "2002" @default.
• W1986890775 type Work @default.
• W1986890775 sameAs 1986890775 @default.
• W1986890775 citedByCount "9" @default.
• W1986890775 countsByYear W19868907752015 @default.
• W1986890775 crossrefType "journal-article" @default.
• W1986890775 hasAuthorship W1986890775A5044444886 @default.
• W1986890775 hasAuthorship W1986890775A5051176970 @default.
• W1986890775 hasAuthorship W1986890775A5060653575 @default.
• W1986890775 hasAuthorship W1986890775A5066533363 @default.
• W1986890775 hasAuthorship W1986890775A5067692511 @default.
• W1986890775 hasAuthorship W1986890775A5079234910 @default.
• W1986890775 hasAuthorship W1986890775A5079794318 @default.
• W1986890775 hasBestOaLocation W19868907751 @default.
• W1986890775 hasConcept C103486182 @default.
• W1986890775 hasConcept C126322002 @default.
• W1986890775 hasConcept C134018914 @default.
• W1986890775 hasConcept C155710745 @default.
• W1986890775 hasConcept C170493617 @default.
• W1986890775 hasConcept C24998067 @default.
• W1986890775 hasConcept C2778468042 @default.
• W1986890775 hasConcept C2778575167 @default.
• W1986890775 hasConcept C2781453256 @default.
• W1986890775 hasConcept C42219234 @default.
• W1986890775 hasConcept C57900726 @default.
• W1986890775 hasConcept C68923441 @default.
• W1986890775 hasConcept C71924100 @default.
• W1986890775 hasConcept C84393581 @default.
• W1986890775 hasConceptScore W1986890775C103486182 @default.
• W1986890775 hasConceptScore W1986890775C126322002 @default.
• W1986890775 hasConceptScore W1986890775C134018914 @default.
• W1986890775 hasConceptScore W1986890775C155710745 @default.
• W1986890775 hasConceptScore W1986890775C170493617 @default.
• W1986890775 hasConceptScore W1986890775C24998067 @default.
• W1986890775 hasConceptScore W1986890775C2778468042 @default.
• W1986890775 hasConceptScore W1986890775C2778575167 @default.
• W1986890775 hasConceptScore W1986890775C2781453256 @default.
• W1986890775 hasConceptScore W1986890775C42219234 @default.
• W1986890775 hasConceptScore W1986890775C57900726 @default.
• W1986890775 hasConceptScore W1986890775C68923441 @default.
• W1986890775 hasConceptScore W1986890775C71924100 @default.
• W1986890775 hasConceptScore W1986890775C84393581 @default.
• W1986890775 hasIssue "1" @default.
• W1986890775 hasLocation W19868907751 @default.
• W1986890775 hasLocation W19868907752 @default.
• W1986890775 hasLocation W19868907753 @default.
• W1986890775 hasOpenAccess W1986890775 @default.
• W1986890775 hasPrimaryLocation W19868907751 @default.

• next